(S)-10-Hydroxycamptothecin cas no:19685-09-7
Synonyms: 10-Hydroxy-CPT;Camptothecin, hydroxy-;1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, hydrate, (S)-;(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Camptothecine, 10-hydroxy- (8CI);Hydroxycamptothecine;1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione-,4-ethyl-4,9-dihydroxy-, (S)- (9CI);
Name(S)-10-Hydroxycamptothecin
CAS19685-09-7
Synonyms10-Hydroxy-CPT;Camptothecin, hydroxy-;1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, hydrate, (S)-;(4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Camptothecine, 10-hydroxy- (8CI);Hydroxycamptothecine;1H-Pyrano(3,4:6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione-,4-ethyl-4,9-dihydroxy-, (S)- (9CI);
Molecular FormulaC20H16N2O5
Molecular Weight364.35
AppearanceYellow solid
Hazard Xi
Risk R36/37/38
Safety
Safety Information of?(S)-10-Hydroxycamptothecin (CAS NO.19685-09-7):
Hazard Codes:Xi?? 
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin?
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing???
WGK Germany:3
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
104mg/kg (104mg/kg) |
? |
Drugs of the Future. Vol. 7, Pg. 629, 1982. |
| rat |
LD |
intravenous |
> 10mg/kg (10mg/kg) |
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
KIDNEY, URETER, AND BLADDER: HEMATURIA |
Cancer Chemotherapy and Pharmacology. Vol. 41, Pg. 257, 1998. |
