8,11-Ethanofuro[2,3-e]naphtho[2,3-c:6,7-c']dipyran-2,6,13(9H)-trione,3,3a,5,8,11,13b-hexahydro-7,8,12,15-tetrahydroxy-5,9-dimethyl-,(3aS,5S,8S,9R,11R,13bS,15R)- cas no:19879-06-2
Synonyms: 8,11-Ethanofuro[2,3-e]naphtho[2,3-c:6,7-c']dipyran-2,6,13(9H)-trione,3,3a,5,8,11,13b-hexahydro-7,8,12,15-tetrahydroxy-5,9-dimethyl-, [3aS-(3aa,5a,8a,9a,11b,13ba,15S*)]-; Granaticin (6CI,7CI,8CI); Antibiotic WR 141; Granaticin A;Granatomycin C; Litmomycin; NSC 77038; WR 141
Name8,11-Ethanofuro[2,3-e]naphtho[2,3-c:6,7-c']dipyran-2,6,13(9H)-trione,3,3a,5,8,11,13b-hexahydro-7,8,12,15-tetrahydroxy-5,9-dimethyl-,(3aS,5S,8S,9R,11R,13bS,15R)-
CAS19879-06-2
Synonyms8,11-Ethanofuro[2,3-e]naphtho[2,3-c:6,7-c']dipyran-2,6,13(9H)-trione,3,3a,5,8,11,13b-hexahydro-7,8,12,15-tetrahydroxy-5,9-dimethyl-, [3aS-(3aa,5a,8a,9a,11b,13ba,15S*)]-; Granaticin (6CI,7CI,8CI); Antibiotic WR 141; Granaticin A;Granatomycin C; Litmomycin; NSC 77038; WR 141
Molecular FormulaC22H20 O10
Molecular Weight444.42
refractive index1.745
Safety Poison by subcutaneous and intraperitoneal routes. Mutation data reported. An antibiotic. When heated to decomposition it emits acrid smoke and irritating fumes.
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MD9100000
- CHEMICAL NAME :
- Granaticin
- CAS REGISTRY NUMBER :
- 19879-06-2
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C22-H20-O10
- MOLECULAR WEIGHT :
- 444.42
- WISWESSER LINE NOTATION :
- T F5 E6 C6666/RW 2AQ W DV GOV KO NV TOTT&&TTJ BQ L1
PQ RQ S1 WQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Bacillus subtilis
- DOSE/DURATION :
- 600 nmol/L
- REFERENCE :
- ZBPHA6 Zentralblatt fuer Bakteriologie, Parasitenkunde,
Infektionskrankheiten und Hygiene, Abteilung I: Medizinisch-Hygienische
Bakteriologie, Virusforschung und Parasitologie, Originale. (Stuttgart, Fed.
Rep. Ger.) V.31-216, 1902-71. For publisher information, see ZMMPAO.
Volume(issue)/page/year: 212,259,1969
