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Oxytetracycline hydrochloride cas no:2058-46-0

Synonyms: 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6b,12aa)]-;1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamidehydrochloride;5-Hydroxytetracycline hydrochloride;5-Hydroxytetracyclinemonohydrochloride;Alamycin;Aquacycline;Duphacycline;Engemycin;Gynamousse;Mepatar;Oxy WS;Oxy-Dumocyclin;Oxybiotic;Oxycyclin;Oxypan;Oxytet;Oxytetrin;TM 5;Terraject;Terramycin hydrochloride;Tetra-Tabilinen;Tetran hydrochloride;Toxinal;Vetilmicin;

Identification
NameOxytetracycline hydrochloride
CAS2058-46-0
Synonyms2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6b,12aa)]-;1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamidehydrochloride;5-Hydroxytetracycline hydrochloride;5-Hydroxytetracyclinemonohydrochloride;Alamycin;Aquacycline;Duphacycline;Engemycin;Gynamousse;Mepatar;Oxy WS;Oxy-Dumocyclin;Oxybiotic;Oxycyclin;Oxypan;Oxytet;Oxytetrin;TM 5;Terraject;Terramycin hydrochloride;Tetra-Tabilinen;Tetran hydrochloride;Toxinal;Vetilmicin;
EINECS(EC#)218-161-2
Molecular FormulaC22H25ClN2O9
Molecular Weight496.9
Chemical Properties
AppearanceYellow crystalline solid
storage temp0-6°C
Safety Data

Hazard Xn:Harmful
Risk R36;R63
Safety

Hazard Codes:?HarmfulXn,IrritantXi
Risk Statements: 63-36-36/37/38?
R36:Irritating to eyes.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 36/37/39-26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.


HS Code 29413000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 100mg/kg (100mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Annals of the New York Academy of Sciences. Vol. 53, Pg. 238, 1950.
mouse LD50 intravenous 100mg/kg (100mg/kg) ? "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 490, 1967.
mouse LD50 oral 6696mg/kg (6696mg/kg) ? Annals of the New York Academy of Sciences. Vol. 53, Pg. 238, 1950.
mouse LD50 subcutaneous 600mg/kg (600mg/kg) ? Annals of the New York Academy of Sciences. Vol. 53, Pg. 245, 1950.
rabbit LDLo intravenous 80mg/kg (80mg/kg) BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 234, 1950.
rat LD50 intravenous 302mg/kg (302mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 234, 1950.
rat LD50 subcutaneous 800mg/kg (800mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 711, 1959.
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supplier list

ORICHEM INTERNATIONAL LTD.
Tel:86-0571-85270505
Address: FLAT E,16/F,1 HUAZHE PLAZA,HANGZHOU,
Shanghai Asarum Biotechnology Co., Ltd
Tel:
Address: Room 404 SiPing road No.1128 YangPu district ShangHai China
Zhejiang Chempharm Industry & Trading Co., Ltd.
Tel:0086-571-87701568 87701600
Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China
SINOCO CHEMICAL CO., LIMITED
Tel:+86-571-81956191, 81956192
Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.
Ningbo Pangs Chem Int'l Co. Ltd.
Tel:+86-(574)-27668808
Address: Floor 21, Building 11, Xintiandi, No. 689, Shiji Road, Ningbo 315040,
Duheng Biotechnology Co., Ltd.
Tel:+86-(21)-51870157
Address: Room 1006 Building B, Oasis Square, North Zhongshan Road, Shanghai 200063,
Yangzhou Lijiang Pharmaceutical Co., Ltd.
Tel:+86-(514)-86510632
Address: Room 1108, Liqiang City Mansion, Jiefang Road, Jiangdu, Jiangsu 225200,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
FarmaSino Pharmaceuticals Co., Ltd.
Tel:+86-(25)-8421-6526
Address: No.100 JianYe Road, Nanjing, Jiangsu 210004,
Ronas Chemicals Ind. Co., Ltd.
Tel:+86-(28)-86082869
Address: Rome International Plaza,Room 09A,19th Floor,NO.210,West Yulong Street, Chengdu, Qingyang District, Sichuan 610072,
Steamline Industries Ltd.
Tel:+91-(22)-40999700, 9833720865
Address: 901/904 Jagdamba Commercial Complex A/2, Near Movitime Theatre, Link Road, Malad (W), Mumbai, Maharashtra 400064,
Farmasino pharmaceuticals(Jiangsu)co.,ltd
Tel:+86-25-86907219
Address: 100 jianye road,nanjing(210004),china
HONGKONG CHEMAPI LIMITED
Tel:+86-186-02659358
Address: ZHENLI ROAD,HEDONG DISTRICT,TIANJIN PRC
HBCChem, Inc.
Tel:+1-510-219-6317
Address:
Hangzhou Starshine Pharmaceutical Co., LTD
Tel:86-571-8696517
Address: Fengqi East Road, Hangzhou, China.

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