Oxytetracycline hydrochloride cas no:2058-46-0
Synonyms: 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6b,12aa)]-;1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamidehydrochloride;5-Hydroxytetracycline hydrochloride;5-Hydroxytetracyclinemonohydrochloride;Alamycin;Aquacycline;Duphacycline;Engemycin;Gynamousse;Mepatar;Oxy WS;Oxy-Dumocyclin;Oxybiotic;Oxycyclin;Oxypan;Oxytet;Oxytetrin;TM 5;Terraject;Terramycin hydrochloride;Tetra-Tabilinen;Tetran hydrochloride;Toxinal;Vetilmicin;
NameOxytetracycline hydrochloride
CAS2058-46-0
Synonyms2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride, [4S-(4a,4aa,5a,5aa,6b,12aa)]-;1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamidehydrochloride;5-Hydroxytetracycline hydrochloride;5-Hydroxytetracyclinemonohydrochloride;Alamycin;Aquacycline;Duphacycline;Engemycin;Gynamousse;Mepatar;Oxy WS;Oxy-Dumocyclin;Oxybiotic;Oxycyclin;Oxypan;Oxytet;Oxytetrin;TM 5;Terraject;Terramycin hydrochloride;Tetra-Tabilinen;Tetran hydrochloride;Toxinal;Vetilmicin;
EINECS(EC#)218-161-2
Molecular FormulaC22H25ClN2O9
Molecular Weight496.9
AppearanceYellow crystalline solid
storage temp0-6°C
Hazard Xn:Harmful
Risk R36;R63
Safety
Hazard Codes:?
Xn,
Xi
Risk Statements: 63-36-36/37/38?
R36:Irritating to eyes.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 36/37/39-26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
HS Code 29413000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LDLo |
intravenous |
100mg/kg (100mg/kg) |
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Annals of the New York Academy of Sciences. Vol. 53, Pg. 238, 1950. |
| mouse |
LD50 |
intravenous |
100mg/kg (100mg/kg) |
? |
"Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 490, 1967. |
| mouse |
LD50 |
oral |
6696mg/kg (6696mg/kg) |
? |
Annals of the New York Academy of Sciences. Vol. 53, Pg. 238, 1950. |
| mouse |
LD50 |
subcutaneous |
600mg/kg (600mg/kg) |
? |
Annals of the New York Academy of Sciences. Vol. 53, Pg. 245, 1950. |
| rabbit |
LDLo |
intravenous |
80mg/kg (80mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: EXCITEMENT |
Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 234, 1950. |
| rat |
LD50 |
intravenous |
302mg/kg (302mg/kg) |
? |
Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 234, 1950. |
| rat |
LD50 |
subcutaneous |
800mg/kg (800mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 711, 1959.
? |
