2078-54-8|DisoprofolProducts Supply - Chemical intermediates Network

Disoprofol cas no:2078-54-8

Synonyms: diprivan; 2,6-Diisopropylphenol; propofol

Identification

NameDisoprofol
CAS2078-54-8
Synonymsdiprivan; 2,6-Diisopropylphenol; propofol
EINECS(EC#)218-206-6
Molecular FormulaC12H18O
Molecular Weight178.27

Chemical Properties

Appearancelight yellow liquid
refractive index1.513-1.515
storage temp0-6°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Poison by intravenous and intraperitoneal routes. Experimental reproductive effects. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and fumes. See also PHENOL.
Hazard Codes:? Harmful Xn
Risk Statements: 22-36/37/38-20/21/22?
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37/39-37/39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S37/39: Wear suitable gloves and eye/face protection.?
S36: Wear suitable protective clothing.
RIDADR: 2810
WGK Germany: 3
HazardClass: 6.1(b)
PackingGroup of Propofol (CAS NO.2078-54-8): III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	30mg/kg (30mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 38, Pg. 1117, 1996.
man	LDLo	intravenous	386mg/kg/14D- (386mg/kg)	LUNGS, THORAX, OR RESPIRATION: PLEURAL THICKENING	Critical Care Medicine. Vol. 23, Pg. 1928, 1995.
man	TDLo	unreported	2857ug/kg/1D- (2.857mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: REGIDITY BEHAVIORAL: IRRITABILITY	Anaesthesia. Vol. 43, Pg. 170, 1988.
mouse	LD50	intraperitoneal	170mg/kg (170mg/kg)	?	Journal of Medicinal and Pharmaceutical Chemistry. Vol. 2, Pg. 201, 1960.
mouse	LD50	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ANALGESIA BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980.
mouse	LD50	oral	1100mg/kg (1100mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.
rabbit	LDLo	intravenous	20mg/kg (20mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SLEEP BEHAVIORAL: MUSCLE WEAKNESS	Journal of Medicinal Chemistry. Vol. 23, Pg. 1350, 1980.
rat	LD50	intravenous	42mg/kg (42mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 21, Pg. 11, 1993.
rat	LD50	oral	500mg/kg (500mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 953, 1995.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

Melone Pharmaceutical Co., Ltd.: Tel:; Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

Zamban Group SpA: Tel:+39-(02)-665241; Address: Via Lillo del Duca 10, Bresso 20091,

Baxter International Inc.: Tel:+1-(847)-948-2000; Address: One Baxter Parkway, Deerfield, Illinois 60015-4625,

Sciencelab.com, Inc.: Tel:+1-(281)-441-4400; Address: 14025, Smith Road, Houston, Texas 77396,

Azocolor Technology Limited: Tel:+86-756-3820661; Address: No 288 Renming Xilu,Zhuhai,China

Taizhou Crene Chempharm Co., Ltd.: Tel:+86-(576)-88813233; Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000,

Wuxi Mizat Chemical Technology Co., Ltd: Tel:+86-(510)-86106900; Address: No.205,zhencheng Road, HI-TECT District, Wuxi, Jiangsu,

Beijing Jinghuayongxin Pharmaceutical Technology Company: Tel:（86）10－67162498; Address: Rm-B504,A. 39, Xingfu dajie, Chongwen District,Beijing,China

ZHONGBEI NORTHLAND BIO-CHEM INDUSTRY CO., LTD.: Tel:+86-452-6197139; Address: SONGLING DISTRICT, JIAGEDAQI CITY, DAXINGANLING, HEILONGJIANG PROVINCE, CHINA

KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD: Tel:86-23-8650081; Address: 32F,Duhe Plaza, Lijiatuo Street, Banan Dist,Chongq

Kaiweidun Fine Chemical Co., Ltd: Tel:86-0311-67690566; Address: shijiazhuang zhongshanlu dajingjie tianzijiali 3haolou

Resolution Ltd: Tel:+86-10-64687818; Address: Room 1123, Gaolan Building,

Disoprofol cas no:2078-54-8

Directory

supplier list