Azocine,octahydro-1-nitroso- cas no:20917-49-1

NameAzocine,octahydro-1-nitroso-
CAS20917-49-1
SynonymsHeptamethylenimine,1-nitroso- (7CI); N-Nitrosoazacyclooctane; N-Nitrosoheptamethyleneimine
Molecular FormulaC7H14 N2 O
Molecular Weight142.23

refractive index1.532

Safety

RTECS: CN4900000
Poison by ingestion and subcutaneous routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When Octahydro-1-nitrosoazocine (CAS NO.20917-49-1) is heated to decomposition ,it emits toxic fumes of NO_x. See also N-NITROSO COMPOUNDS.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
hamster	LD50	subcutaneous	220mg/kg (220mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	JNCI, Journal of the National Cancer Institute. Vol. 61, Pg. 239, 1978.
rat	LD50	oral	283mg/kg (283mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"	Proceedings of the Society for Experimental Biology and Medicine. Vol. 130, Pg. 945, 1969.