20977-05-3|Escin monosodium saltProducts Supply - Chemical intermediates Network

Escin monosodium salt cas no:20977-05-3

Synonyms: Sodium Aescinate; Sodium escinate

Identification

NameEscin monosodium salt
CAS20977-05-3
SynonymsSodium Aescinate; Sodium escinate
EINECS(EC#)244-133-4
Molecular FormulaC55H85O24?Na
Molecular Weight1124.2246

Safety Data

Safety

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. When Escin, sodium salt (CAS NO.20977-05-3) is heated to decomposition, it emits toxic fumes of Na₂O. See also SAPONIN and ESCIN; α-ESCIN; β-ESCIN; ESCIN TRIETHANOLAMINE SALT.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	intravenous	9130ug/kg (9.13mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.
mouse	LD50	intraperitoneal	8299ug/kg (8.299mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 114, 1974.
mouse	LD50	intravenous	4730mg/kg (4730mg/kg)		Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 22, Pg. 87, 1987.
mouse	LD50	oral	134mg/kg (134mg/kg)		Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 22, Pg. 87, 1987.
mouse	LD50	subcutaneous	92530ug/kg (92.53mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 114, 1974.
rabbit	LD50	intravenous	5mg/kg (5mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960. Link to PubMed
rat	LD50	intraperitoneal	9180ug/kg (9.18mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 114, 1974.
rat	LD50	intravenous	8131ug/kg (8.131mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 114, 1974.
rat	LD50	oral	400mg/kg (400mg/kg)		Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 22, Pg. 87, 1987.
rat	LD50	subcutaneous	131mg/kg (131mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 114, 1974.

supplier list

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Wuhan Dahua Weiye Pharmaceutical Co.,Ltd: Tel:86-27-59335372; Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China

Finetech Industry limited.: Tel:86-27-87465837; Address: chukang Road, Wuhan, Hubei 430073,

Chengdu Herbpurify CO.,LTD: Tel:86-28-85249238; Address: No.88 Keyuan Road,Chengdu,Sichuan,China

Shanghai Meicheng Chemical Co., Ltd.: Tel:86-21-50677091; Address: Room 302, Building 7, No.1000, Jinhai Road, Shanghai, 201206, China

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Zhengzhou Tongguang Chemical Science C，.Ltd: Tel:-86-371-60107515; Address: No.120 Huanghe Road Zhengzhou

Shanghai Forever Biotech Co., Ltd.: Tel:+86-(21)-6973-4790; Address:

Baoji Herbest Bio-Tech Co., Ltd: Tel:+86-917-3591456; Address: No 2 Xifeng Road Baoji City

Baoji Guokang Bio-Technology Co.,Ltd: Tel:+86-917-8835516; Address: 3 High-tech high-tech zones, Baoji City Road, No. 10

Kouting Chemical Co.,Ltd: Tel:+86-(21)-58116473; Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,

Alchemist Worldwide Ltd.: Tel:+86-(25)-5119-2301; Address: Shangyuan Street, 863# Dongcheng Jiayuan 10dong-602, Jiangning Area, Nanjing, Jiangsu,

Tianjin Lonma Co., Ltd: Tel:+86-(22)-24712728; Address: The South of Cheng Linzhuang Road, Hedong District, Tianjin 300162,

SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Escin monosodium salt cas no:20977-05-3

Directory

supplier list