Phosphorothioic acid,O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester cas no:2104-96-3

NamePhosphorothioic acid,O-(4-bromo-2,5-dichlorophenyl) O,O-dimethyl ester
CAS2104-96-3
Synonyms4-Bromo-2,5-dichlorophenyldimethyl phosphorothionate; Bromofos; Bromophos; Bromophos-methyl; Bromovur;Cela S 1942; Drillzid; EL 400; Metabrom; NSC 527602; Nexion; Nexion 25WP;Nexion 40; Nexion 40EC; Nexion 5G; Nexion LC 40; O,O-DimethylO-(2,5-dichloro-4-bromophenyl) thiophosphate; O,O-DimethylO-(4-bromo-2,5-dichlorophenyl) phosphorothioate; O,O-DimethylO-(4-bromo-2,5-dichlorophenyl) phosphorothionate;O,O-Dimethyl-O-(2,5-dichloro-4-bromophenyl)phosphorothioate;O-(4-Bromo-2,5-dichlorophenyl) O,O-dimethyl phosphorothioate; OMS 658; Omexan;S 1942; Sovinexion
EINECS(EC#)218-277-3
Molecular FormulaC8H8 Br Cl2 O3 P S
Molecular Weight366.00

refractive index1.582
storage temp0-6°C

Hazard Xn: Harmful;N: Dangerous for the environment;
Risk R22;R50/53
Safety

Moderately toxic by ingestion, skin contact, intraperitoneal, and possibly other routes. Human systemic effects by ingestion: miosis, muscle contraction, hypermotility, diarrhea. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO_x, PO_x, Br⁻, and Cl⁻. 
Hazard Codes:
Xn
N
Risk Statements:
R22:Harmful if swallowed. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S2:Keep out of the reach of children. 
S36:Wear suitable protective clothing. 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN3077 9/PG 3
RTECS: TE7175000

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	oral	750mg/kg (750mg/kg)		Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
chicken	LD50	oral	9700mg/kg (9700mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
guinea pig	LD50	oral	1500mg/kg (1500mg/kg)	behavioral: muscle weakness gastrointestinal: ulceration or bleeding from stomach gastrointestinal: ulceration or bleeding from large intestine	Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
mammal (species unspecified)	LD50	skin	2820mg/kg (2820mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(7), Pg. 34, 1977.
mammal (species unspecified)	LD50	unreported	3750mg/kg (3750mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(8), Pg. 82, 1976.
mouse	LD50	intraperitoneal	1040mg/kg (1040mg/kg)	behavioral: somnolence (general depressed activity) behavioral: food intake (animal) lungs, thorax, or respiration: respiratory depression	Archiv fuer Toxikologie. Vol. 22, Pg. 36, 1966.
mouse	LD50	oral	2829mg/kg (2829mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rabbit	LD50	oral	720mg/kg (720mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rabbit	LD50	skin	2181mg/kg (2181mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 29, 1976.
rat	LD50	intraperitoneal	1625mg/kg (1625mg/kg)		Defense des Vegetaux. Vol. 32, Pg. 40, 1978.
rat	LD50	oral	1600mg/kg (1600mg/kg)		Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat	LD50	skin	> 5gm/kg (5000mg/kg)		Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.
rat	LD50	subcutaneous	> 12gm/kg (12000mg/kg)	behavioral: changes in motor activity (specific assay) skin and appendages (skin): hair: other	Azabu Juika Daigaku Kenkyu Hokoku. Bulletin of Azabu Veterinary College. Vol. 30, Pg. 213, 1975.
women	TDLo	oral	152mg/kg (152mg/kg)	sense organs and special senses: miosis (pupillary constriction): eye behavioral: muscle contraction or spasticity) gastrointestinal: "hypermotility, diarrhea"	Journal of Toxicology, Clinical Toxicology. Vol. 29, Pg. 203, 1991.