21187-98-4|GliclazideProducts Supply - Chemical intermediates Network

Gliclazide cas no:21187-98-4

Synonyms: Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;

Identification

NameGliclazide
CAS21187-98-4
SynonymsUrea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;
EINECS(EC#)244-260-5
Molecular FormulaC₁₅H₂₁N₃O₃S
Molecular Weight323.41054

Chemical Properties

Appearancewhite powder
refractive index1.623
storage tempKeep tightly closed.

Safety Data

Hazard Xn,Xi
Risk R21
Safety

Hazard Codes: Harmful

Xn,

Xi
Risk Statements:21-36/38-46-62-63
R21:Harmful in contact with skin?
R36/38:Irritating to eyes and skin
R46:May cause heritable genetic damage?
R62:Possible risk of impaired fertility?
R63:Possible risk of harm to the unborn child?
Safety Statements:25-26-36/37-53
S25:Avoid contact with eyes?
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves???
S53:Avoid exposure - obtain special instruction before use
WGK Germany:2
RTECS:YT4500000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)	?	European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 81, 1982.
mouse	LD50	intravenous	295mg/kg (295mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
mouse	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
mouse	LD50	subcutaneous	1034mg/kg (1034mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	intravenous	382mg/kg (382mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
rat	LD50	subcutaneous	> 1gm/kg (1000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
women	TDLo	oral	9600ug/kg/24D (9.6mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Internal Medicine. Vol. 33, Pg. 163, 1994.

supplier list

Shandong Novatech Pharmaceutical Co., Ltd.: Tel:+86-531-55582725; Address: R801,Lianggu Building, No.6 Qilihe Road,

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

ZHEJIANG CHEMIALS IM & EXP CORP.: Tel:86-571-87048079; Address: No.37,Qingchun Road,Hangzhou,China

IFFECT CHEMPHAR CO., LTD.: Tel:86-25-84679300; Address: 509, FuXin International Building, No.359 HongWu R

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SHENYANG CHENGTAI FINE CHEMICALS FACTORY: Tel:+971-7-2461461; Address: RAK Air port road,RAK

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Yixing Jiangshan Bio-tech Co., Ltd. (formerly Yix...: Tel:; Address: Rm.205,7# Building, XingHua XinCun,East JieFang Road, Yixing, Jiangsu, China

Depew Fine Chemical Co.,Ltd.: Tel:+86-571-87630650, 87630656, 87630657; Address: Room 202,No.317 Wantang Road,Hangzhou,China

Kingland Chemicals Company Limited: Tel:+86-571-87211518,87229835; Address: Room No. 1806-1808, Jinfeng Mansion, No.281 Zhong He Zhong Road, Hangzhou, China.

Beijing Sinowall Science & Technology Co.,Ltd.: Tel:; Address: Room210,East Build 9,NO.83 Fuxing Road,Haidian District, Beijing

Jiangsu Guotai International Group: Tel:; Address: 10-11/F, Guotai Bldg, 43 Renmin Road, Zhangjiagang, Jiangsu Province, China 215600.

CIDIC Co.,Ltd.: Tel:; Address: 15/F, HODO International Plaza, 531 Zhongshan Road, Wuxi, China

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Gliclazide cas no:21187-98-4

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