21187-98-4|GliclazideProducts Supply - Chemical intermediates Network

Gliclazide cas no:21187-98-4

Synonyms: Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;

Identification

NameGliclazide
CAS21187-98-4
SynonymsUrea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;
EINECS(EC#)244-260-5
Molecular FormulaC₁₅H₂₁N₃O₃S
Molecular Weight323.41054

Chemical Properties

Appearancewhite powder
refractive index1.623
storage tempKeep tightly closed.

Safety Data

Hazard Xn,Xi
Risk R21
Safety

Hazard Codes: Harmful

Xn,

Xi
Risk Statements:21-36/38-46-62-63
R21:Harmful in contact with skin?
R36/38:Irritating to eyes and skin
R46:May cause heritable genetic damage?
R62:Possible risk of impaired fertility?
R63:Possible risk of harm to the unborn child?
Safety Statements:25-26-36/37-53
S25:Avoid contact with eyes?
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves???
S53:Avoid exposure - obtain special instruction before use
WGK Germany:2
RTECS:YT4500000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)	?	European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 81, 1982.
mouse	LD50	intravenous	295mg/kg (295mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
mouse	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
mouse	LD50	subcutaneous	1034mg/kg (1034mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	intravenous	382mg/kg (382mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
rat	LD50	subcutaneous	> 1gm/kg (1000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
women	TDLo	oral	9600ug/kg/24D (9.6mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Internal Medicine. Vol. 33, Pg. 163, 1994.

supplier list

Shandong Novatech Pharmaceutical Co., Ltd.: Tel:+86-531-55582725; Address: R801,Lianggu Building, No.6 Qilihe Road,

Saniver Limited: Tel:; Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.

Laboratoire SUBSTIPHARM: Tel:; Address:

CFM Oskar Tropitzsch: Tel:+49-(9231)-9619-0; Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,

Matrix Laboratories Ltd.: Tel:+91-(40)-27700363; Address: 1-151/1, IV Floor, Sairam Towers, Alexander Road, Secunderabad, Andhra Pradesh 500 003,

Micro Orgo Chem: Tel:+91-(22)-24448834; Address: 28, Lohar Chawl, Mahim, Mumbai, Maharashtra 400016,

Wuhan Pharma Chemical Co., Ltd.: Tel:+86-27-87711369; Address: 430071

Sol Chem Marketing & Research Co., Ltd.: Tel:+86-(574)-81910677; Address: Fine Chemical Park, Ningbo, Zhejiang,

CNSC Fortune Way Company: Tel:+86-(10)-84641677; Address: 4, Huixin Dongjie, ChaoYang District, Beijing 100029,

Varda Biotech Pvt. Ltd.: Tel:+91-(22)-6693 5686; Address: #110 & 111 Kartik Complex, New Link Road, Andheri (W), Mumbai, Maharashtra 400 053,

ACIC Fine Chemicals Inc.: Tel:+1-(800)-265-6727; Address: 11772 West Sample Road, Coral Springs, Florida 33065,

Beijing Sinowall Science & Technology Co., Ltd.: Tel:+86-(10)-5160-6228; Address: Room210,East Build 9,NO.83 Fuxing Road,Haidian District, Beijing 100856,

Tianjin Hi-Tesion Bio&Chem Co., Ltd.: Tel:+86-(22)-2372-5099; Address: C1506, Wanhao Mansion, No.333 Binshuixi Road, Nankai District, Tianjin 300381,

Parchem - Fine & Specialty Chemicals: Tel:+1-(914)-654-6800, 800-282-3982; Address: 415 Huguenot Street, New Rochelle, New York 10801,

Farmasino pharmaceuticals(Jiangsu)co.,ltd: Tel:+86-25-86907219; Address: 100 jianye road,nanjing(210004),china

Gliclazide cas no:21187-98-4

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