21187-98-4|GliclazideProducts Supply - Chemical intermediates Network

Gliclazide cas no:21187-98-4

Synonyms: Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;

Identification

NameGliclazide
CAS21187-98-4
SynonymsUrea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI);Cyclopenta[c]pyrrole, benzenesulfonamide deriv.;1-(Hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Diabezidum;Diabyl;Diamicron;Diaprel;Glimicron;Glinormax;Glyzide;N-(4-Methylbenzenesulfonyl)-N'-[3-azabicyclo(3,3,0)oct-3-yl]urea;S1702;S 852;SE 1702;Benzenesulfonamide,N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-;
EINECS(EC#)244-260-5
Molecular FormulaC₁₅H₂₁N₃O₃S
Molecular Weight323.41054

Chemical Properties

Appearancewhite powder
refractive index1.623
storage tempKeep tightly closed.

Safety Data

Hazard Xn,Xi
Risk R21
Safety

Hazard Codes: Harmful

Xn,

Xi
Risk Statements:21-36/38-46-62-63
R21:Harmful in contact with skin?
R36/38:Irritating to eyes and skin
R46:May cause heritable genetic damage?
R62:Possible risk of impaired fertility?
R63:Possible risk of harm to the unborn child?
Safety Statements:25-26-36/37-53
S25:Avoid contact with eyes?
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves???
S53:Avoid exposure - obtain special instruction before use
WGK Germany:2
RTECS:YT4500000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	> 1gm/kg (1000mg/kg)	?	European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 81, 1982.
mouse	LD50	intravenous	295mg/kg (295mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
mouse	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
mouse	LD50	subcutaneous	1034mg/kg (1034mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	intravenous	382mg/kg (382mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat	LD50	oral	3gm/kg (3000mg/kg)	?	Indian Drugs. Vol. 15, Pg. 161, 1978.
rat	LD50	subcutaneous	> 1gm/kg (1000mg/kg)	?	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
women	TDLo	oral	9600ug/kg/24D (9.6mg/kg)	LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED	Internal Medicine. Vol. 33, Pg. 163, 1994.

supplier list

Saniver Limited: Tel:; Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.

ORICHEM INTERNATIONAL LTD.: Tel:86-0571-85270505; Address: FLAT E,16/F,1 HUAZHE PLAZA,HANGZHOU,

INFA S.P.A.: Tel:+39-02-777281; Address: Via Salvini 10, 20122 Milan (Italy)

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Sunasia Co., Ltd.: Tel:; Address: Suite 1503, 15Fl., Huijin Mansion, No. 77 He Yi Road, Ningbo 315000 China

Jiangsu Guotai International Group: Tel:; Address: 10-11/F, Guotai Bldg, 43 Renmin Road, Zhangjiagang, Jiangsu Province, China 215600.

Taizhou Taifeng Chemical Co., Ltd.: Tel:; Address: Jiaojiang District, Taizhou City, Zhejiang Province, China

Starview International Limited: Tel:86-571-88925295 88218645 88920965; Address: 2ND FLOOR, NO.111, YUYUN ROAD, HANGZHOU, ZHEJIANG, CHINA

Ningbo Double Sun Pharmaceutical CO., LTD.: Tel:+86-574-86818018; Address: 5# Nan Hai Rd. Bei Lun Dist. Ningbo, Zhejiang, China

Galenicum Health SL: Tel:+34 93 201 17 50; Address: Diagonal 572, Principal 2C 08021 Barcelona - Spain

Lianyungang Ruidong International Trade Co., Ltd.: Tel:; Address: Room D11, 4th floor, Xinpulonghe Building, Lianyungang, Jiangsu Province, China

Praevideo LLC: Tel:+36-(1)-347-0332; Address: Baross U. 46, Budapest H 1192,

Lake Chemicals Pvt. Ltd.: Tel:+91-(80)-41379500; Address: 5th Floor, Laxmi Narayan Complex, No. 10/1, Palace Road, Bangalore, Karnataka 560052,

A.S. Chemical Laboratories Inc.: Tel:+1-(905)-669-7472; Address: 67- 50 Pippin road, Concord, Ontario L4K 4M4,

Wuhan Pharma Chemical Co., Ltd.: Tel:+86-27-87711369; Address: 430071

Gliclazide cas no:21187-98-4

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