21679-14-1|9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro-Products Supply

9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro- cas no:21679-14-1

Synonyms: Adenine,9-b-D-arabinofuranosyl-2-fluoro- (8CI);2-Fluoro Ara-A;2-Fluoro-9-b-D-arabinofuranosyladenine;2-Fluoroadenine arabinoside;9-b-D-Arabinofuranosyl-2-fluoroadenine;9-b-D-Arabinosyl-2-fluoroadenine;F-ara-A;NSC 118218;NSC 118218H;Fludarabine Base;

Identification

Name9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro-
CAS21679-14-1
SynonymsAdenine,9-b-D-arabinofuranosyl-2-fluoro- (8CI);2-Fluoro Ara-A;2-Fluoro-9-b-D-arabinofuranosyladenine;2-Fluoroadenine arabinoside;9-b-D-Arabinofuranosyl-2-fluoroadenine;9-b-D-Arabinosyl-2-fluoroadenine;F-ara-A;NSC 118218;NSC 118218H;Fludarabine Base;
EINECS(EC#)244-525-5
Molecular FormulaC₁₀H₁₂FN₅O₄
Molecular Weight285.23

Chemical Properties

Appearancewhite solid
refractive index1.876
storage temp2-8°C

Safety Data

Risk R23/24/25;R36/37/38;R39

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU6207000

CHEMICAL NAME :: Adenine, 9-beta-D-arabinofuranosyl-2-fluoro-

CAS REGISTRY NUMBER :: 21679-14-1

LAST UPDATED :: 198909

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H12-F-N5-O4

MOLECULAR WEIGHT :: 285.27

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ GF IZ D- BT5OTJ CQ DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: DNA inhibition

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 100 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 210,291,1989

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