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Home > products > 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-

1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)- cas no:2188-68-3

Synonyms: 1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)- (9CI);Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1a,2b)-;Lycoran-1a,2b-diol, 3,3a-didehydro-, hydrochloride (8CI);Licorin hydrochloride;

Identification
Name1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride (1:1), (1S,2S,12bS,12cS)-
CAS2188-68-3
Synonyms1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol,2,4,5,7,12b,12c-hexahydro-, hydrochloride, (1S,2S,12bS,12cS)- (9CI);Galanthan-1,2-diol, 3,12-didehydro-9,10-[methylenebis(oxy)]-, hydrochloride, (1a,2b)-;Lycoran-1a,2b-diol, 3,3a-didehydro-, hydrochloride (8CI);Licorin hydrochloride;
Molecular FormulaC16H17NO4.HCl
Molecular Weight323.77142
Chemical Properties
Appearancefine crystal powder.
storage temp2-8°C
Safety Data

Hazard T: Toxic;
Risk R25
Safety

Hazard Codes of Lycorine hydrochloride (CAS NO.2188-68-3): ToxicT
Risk Statements: 25 
R25: Toxic if swallowed.
Safety Statements: 45 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 117mg/kg (117mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 intravenous 123mg/kg (123mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.
mouse LD50 oral 230mg/kg (230mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 21, 1958.

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