2H-1,3,2-Oxazaphosphorin-2-amine,N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide cas no:22089-22-1

Name2H-1,3,2-Oxazaphosphorin-2-amine,N,N,3-tris(2-chloroethyl)tetrahydro-, 2-oxide
CAS22089-22-1
Synonyms2H-1,3,2-Oxazaphosphorine,2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)tetrahydro-, 2-oxide (8CI);3-(2-Chloroethyl)-2-[bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine2-oxide; Asta Z 4828; Ixoten; NSC 109723; Trifosfamide; Trilofosfamida;Trilophosphamide; Triphosphamide; Trisfosfamide; Trofosfamid; Trofosfamide; Trophosphamid;Trophosphamide; Z 4828
EINECS(EC#)244-770-8
Molecular FormulaC9H18 Cl3 N2 O2 P
Molecular Weight323.61

refractive index1.518

Safety

Poison by intraperitoneal, subcutaneous, and intravenous routes. Moderately toxic by ingestion. Human mutation data reported. Human systemic effects by unspecified routes: hematuria, leukopenia, and thrombocytopenia. When heated to decomposition it emits very toxic fumes of Cl⁻, NO_x, and PO_x.

1.		mma-esc 10 mmol/L		ARTODN    Archives of Toxicology. 33 (1975),225.
2.		sln-dmg-unr 1 mmol/L/24H		MUREAV    Mutation Research. 33 (1975),221.
3.		cyt-hmn:leu 100 mg/L		HUMAA7    Humangenetik. 5 (1968),321.
4.		cyt-rat-ipr 25 mg/kg		HUMAA7    Humangenetik. 5 (1968),321.
5.		mnt-mus-ipr 80 mg/kg/24H		MUREAV    Mutation Research. 56 (1978),319.
6.		cyt-ham-ipr 3300 µg/kg		ARTODN    Archives of Toxicology. 38 (1977),35.
7.		unr-hmn TDLo:50 mg/kg:BLD,KID		SAMJAF    South African Medical Journal. 53 (1978),886.
8.		orl-rat LD50:202 mg/kg		MDACAP    Medicamentos de Actualidad. 13 (1977),115.
9.		scu-rat LD50:210 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),922.
10.		ivn-rat LD50:90 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 23 (1973),922.
11.		orl-mus LD50:464 mg/kg		MDACAP