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1H-Imidazole-1-carboxylicacid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester cas no:22232-54-8

Synonyms: 4-Imidazoline-1-carboxylicacid, 3-methyl-2-thioxo-, ethyl ester (6CI,8CI);1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline;1-Methyl-3-carbethoxy-2-thioglyoxalone;3-Carbethoxymercapto-1-methylimidazole;3-Carbethoxythio-1-methylglyoxaline;3-Carbethoxythio-1-methyliminazole;Athyromazole;Basolest;CG 1;Carbethoxymethimazole;Ethyl 3-methyl-2-thioimidazoline-1-carboxylate;Ethyl 3-methyl-2-thioxo-D4-imidazoline-1-carboxylate;Neo-Thyreostat;Neomercazole;Tyrazol;

Identification
Name1H-Imidazole-1-carboxylicacid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester
CAS22232-54-8
Synonyms4-Imidazoline-1-carboxylicacid, 3-methyl-2-thioxo-, ethyl ester (6CI,8CI);1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline;1-Methyl-3-carbethoxy-2-thioglyoxalone;3-Carbethoxymercapto-1-methylimidazole;3-Carbethoxythio-1-methylglyoxaline;3-Carbethoxythio-1-methyliminazole;Athyromazole;Basolest;CG 1;Carbethoxymethimazole;Ethyl 3-methyl-2-thioimidazoline-1-carboxylate;Ethyl 3-methyl-2-thioxo-D4-imidazoline-1-carboxylate;Neo-Thyreostat;Neomercazole;Tyrazol;
EINECS(EC#)244-854-4
Molecular FormulaC7H10N2O2S
Molecular Weight186.23
Chemical Properties
refractive index1.611
Sensitive Light Sensitive
Safety Data

Risk R22

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ2441000
CHEMICAL NAME :
4-Imidazoline-1-carboxylic acid, 3-methyl-2-thioxo-, ethyl ester
CAS REGISTRY NUMBER :
22232-54-8
BEILSTEIN REFERENCE NO. :
0144339
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C7-H10-N2-O2-S
MOLECULAR WEIGHT :
186.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
703 mg/kg/17W-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Ear) - change in acuity Sense Organs and Special Senses (Ear) - tinnitus
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
25 mg/kg/6W-I
TOXIC EFFECTS :
Liver - hepatitis (hepatocellular necrosis), diffuse
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
23 mg/kg/5W-I
TOXIC EFFECTS :
Liver - jaundice, cholestatic
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
1 mg/kg/1D-I
TOXIC EFFECTS :
Liver - jaundice, other or unclassified

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
1 gm/L
REFERENCE :
CHINAG Chemistry and Industry (London). (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.1- 1923- Volume(issue)/page/year: (21),847,1980

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