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Phosphoric acid,(1Z)-2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester cas no:22248-79-9

Synonyms: Phosphoricacid, 2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester, (Z)-;Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl ester, (Z)-(8CI);(Z)-Tetrachlorovinphos;CVMP;Debantic;Gardicide;Gardona;Rabon;Rabond;SD 8447;Stirofos;Stirophos;Stitifos;Tetrachlorvinfos;Vinfos;cis-Gardona;

Identification
NamePhosphoric acid,(1Z)-2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester
CAS22248-79-9
SynonymsPhosphoricacid, 2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester, (Z)-;Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl ester, (Z)-(8CI);(Z)-Tetrachlorovinphos;CVMP;Debantic;Gardicide;Gardona;Rabon;Rabond;SD 8447;Stirofos;Stirophos;Stitifos;Tetrachlorvinfos;Vinfos;cis-Gardona;
EINECS(EC#)244-865-4
Molecular FormulaC10H9Cl4O4P
Molecular Weight365.96
Chemical Properties
AppearanceColorless crystals or white powder.
storage temp0-6°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard N: Dangerous for the environment;Xn: Harmful;F: Flammable;
Risk R21/22
Safety

Hazard Codes: HarmfulXn,DangerousN,FlammableF
Risk Statements: 21/22-50/53-36-20/21/22-11
R21/22:Harmful in contact with skin and if swallowed. 
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R36:Irritating to eyes. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R11:Highly flammable.
Safety Statements: 36-60-61-36/37-16
S36:Wear suitable protective clothing. 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S36/37:Wear suitable protective clothing and gloves. 
S16:Keep away from sources of ignition.
RIDADR: UN 3077 9/PG 3
RTECS: TB9100000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 100mg/kg (100mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
cat LC inhalation > 290mg/m3/4H (290mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(4), Pg. 50, 1975.
cattle LD50 oral 360mg/kg (360mg/kg)   Veterinariya. Veterinary Science. Vol. 57(5), Pg. 55, 1981.
chicken LD50 oral 2528mg/kg (2528mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: ATAXIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 11, 49.
duck LD50 oral > 2gm/kg (2000mg/kg)   Pesticide Manual. Vol. 9, Pg. 802, 1991.
guinea pig LC inhalation > 854mg/m3 (854mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(1), Pg. 47, 1987.
guinea pig LD50 intraperitoneal > 5gm/kg (5000mg/kg)   Pesticide Science. Vol. 3, Pg. 517, 1972.
guinea pig LD50 oral 1600mg/kg (1600mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(1), Pg. 47, 1987.
mammal (species unspecified) LD50 unreported 4gm/kg (4000mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 315, 1971.
mouse LC inhalation > 290mg/m3/4H (290mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(4), Pg. 50, 1975.
mouse LD50 oral 1379mg/kg (1379mg/kg)   Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 21, Pg. 65, 1987.
mouse LD50 skin > 7500mg/kg (7500mg/kg)   Yakkyoku. Pharmacy. Vol. 37, Pg. 427, 1986.
rabbit LC inhalation > 290mg/m3/4H (290mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(4), Pg. 50, 1975.
rabbit LD50 skin > 2500mg/kg (2500mg/kg)   Journal of Agricultural and Food Chemistry. Vol. 14, Pg. 352, 1966.
rabbit LD50 subcutaneous > 5gm/kg (5000mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 4, Pg. 113, 1969.
rat LC inhalation > 854mg/m3 (854mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(1), Pg. 47, 1987.
rat LD50 oral 480mg/kg (480mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Pesticide Science. Vol. 3, Pg. 517, 1972.
rat LD50 skin 1500mg/kg (1500mg/kg)   Pesticide Science. Vol. 3, Pg. 517, 1972.
rat LD50 unreported 7473mg/kg (7473mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(4), Pg. 32, 1986.

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Engineering Research Center of Pesticide, Heilongjiang Province
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Ascot International Ltd
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Address: Welcroft Street, Stockport, Cheshire SK1 3DF,

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