22345-47-7|TofisopamProducts Supply - Chemical intermediates Network

Tofisopam cas no:22345-47-7

Synonyms: 1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine;7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine;EGYT 341;Grandaxin;Seriel;

Identification

NameTofisopam
CAS22345-47-7
Synonyms1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine;7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine;EGYT 341;Grandaxin;Seriel;
EINECS(EC#)244-922-3
Molecular FormulaC₂₂H₂₆N₂O₄
Molecular Weight382.50

Chemical Properties

Appearancewhite solid
refractive index1.558

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn: Harmful;N: Dangerous for the environment;
Risk R22;R50
Safety

Hazard Codes: Harmful Xn Dangerous N
Risk Statements: 22-50
R22:Harmful if swallowed.
R50:Very toxic to aquatic organisms.
Safety Statements: 60-61
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DE9540000
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1950mg/kg (1950mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
mouse	LD50	intravenous	415mg/kg (415mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
mouse	LD50	oral	3800mg/kg (3800mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
rat	LD50	intraperitoneal	1270mg/kg (1270mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
rat	LD50	intravenous	103mg/kg (103mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
rat	LD50	oral	825mg/kg (825mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 547, 1981.

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KINFON Pharmaceutical and Chemical Service: Tel:+86-(21)-58871570; Address: No.331, Dongyuan San Cun, 978# of Pudong South Rd., Shanghai 200120,

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

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Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Hangzhou Dayangchem Co., Ltd.: Tel:86-571-88938639; Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

Qingdao happy biological technology co., LTD: Tel:86-310-7123336; Address: Room NO.5126 shibei district xing-an road 29 Qi

Qingdao happy biological technology co., LTD: Tel:86-310-7123336; Address: Room NO.5126 shibei district xing-an road 29 Qi

Zhejiang Haiqiang Chemical Co.,Ltd.: Tel:86-571-86960370; Address: 5/F, Around Town North Road,No. 10, Hangzhou, Zhejiang,China

Shanghai Forever Synthesis Co.,Ltd.: Tel:86-21-61124658; Address: Nianjiabang Rd, Pudong, Shanghai

Rosewell Industry Co., Ltd: Tel:86-519-86202821; Address: Qixing building, Mingxin road, Changzhou,Jiangsu,China

Andexin industrial Co.,Limited: Tel:86-411-39074598; Address: No.98,Shengli road,,Jinzhou district,

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Shin Nippon Yakugyo Co.,Ltd.: Tel:81-3-3667-5941; Address: 11-7, Nihonbashi-Tomizawacho Chuo-Ku, Tokyo Japan

Suqian Mingyuan Technology Development Co.Ltd: Tel:+86-527-82860866; Address: A27 Building,NO.88 Fumin Road,Economic Development Zone,Suqian,Jiangsu,China

Tofisopam cas no:22345-47-7

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