1H-Imidazole-1-acetamide,N-(2-hydroxyethyl)-2-nitro- cas no:22668-01-5

Name1H-Imidazole-1-acetamide,N-(2-hydroxyethyl)-2-nitro-
CAS22668-01-5
SynonymsImidazole-1-acetamide,N-(2-hydroxyethyl)-2-nitro- (8CI); Etanidazole; NSC 301-467; Radinyl; SR 2508
Molecular FormulaC7H10 N4 O4
Molecular Weight214.21

refractive index1.645
storage temp2-8°C

Hazard Xi: Irritant;
Risk 36/37/38
Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38: N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide (CAS NO.22668-01-5) is irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: NI3355000

Moderately toxic by intravenous and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	unreported	4900mg/kg (4900mg/kg)		Gan to Kagaku Ryoho. Cancer and Chemotherapy. Vol. 16, Pg. 1399, 1989.
mouse	LD50	intraperitoneal	3300mg/kg (3300mg/kg)		Radiation Research. Vol. 91, Pg. 186, 1982.
mouse	LD50	intravenous	4100mg/kg (4100mg/kg)		Japanese Journal of Cancer Research. Vol. 80, Pg. 113, 1989.
mouse	LD50	unreported	4900mg/kg (4900mg/kg)		United States Patent Document. Vol. 4371540,
rat	LD50	intravenous	3716mg/kg (3716mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) MUSCULOSKELETAL: OTHER CHANGES	Toxicologist. Vol