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Phosphorothioic acid,O,O-dimethyl S-[2-[[1-methyl-2-(methylamino)-2-oxoethyl]thio]ethyl] ester cas no:2275-23-2

Synonyms: Phosphorothioicacid, O,O-dimethyl ester, S-ester with 2-[(2-mercaptoethyl)thio]-N-methylpropionamide(7CI,8CI); Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothiolate;Kilval; O,O-Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothioate;RP 9895; Vamidoate; Vamidothion; XMC

Identification
NamePhosphorothioic acid,O,O-dimethyl S-[2-[[1-methyl-2-(methylamino)-2-oxoethyl]thio]ethyl] ester
CAS2275-23-2
SynonymsPhosphorothioicacid, O,O-dimethyl ester, S-ester with 2-[(2-mercaptoethyl)thio]-N-methylpropionamide(7CI,8CI); Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothiolate;Kilval; O,O-Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothioate;RP 9895; Vamidoate; Vamidothion; XMC
EINECS(EC#)218-894-8
Molecular FormulaC8H18 N O4 P S2
Molecular Weight287.36
Chemical Properties
AppearanceColorless needles.
refractive index1.507
storage temp0-6°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;N: Dangerous for the environment;
Risk R21;R25;R50
Safety

Poison by ingestion and skin contact. Mutation data reported. When heated to decomposition it emits very toxic fumes of POx, SOx, and NOx.
Hazard Codes:
ToxicT
DangerousN
HarmfulXn
FlammableF
Risk Statements:
R21:Harmful in contact with skin. 
R25 :Toxic if swallowed. 
R50:Very toxic to aquatic organisms. 
R36:Irritating to eyes. 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R11:Highly flammable.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets. 
S16:Keep away from sources of ignition.
RIDADR: UN 2811
RTECS: TF7900000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 35mg/kg (35mg/kg)   Pesticide Manual. Vol. 9, Pg. 856, 1991.
cat LD50 unreported 117mg/kg (117mg/kg)

behavioral: ataxia behavioral: coma kidney, ureter, and bladder: urine volume increased

Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(3), Pg. 107, 1976.
dog LD50 oral 110mg/kg (110mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig LD50 oral 85mg/kg (85mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig LD50 unreported 85mg/kg (85mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
mouse LD50 oral 40mg/kg (40mg/kg)

behavioral: tremor
behavioral: convulsions or effect on seizure threshold gastrointestinal: changes in structure or function of salivary glands

Meditsinskii Zhurnal Uzbekistana. Vol. (8), Pg. 65, 1972.
mouse LD50 skin 1460mg/kg (1460mg/kg)   Yakkyoku. Pharmacy. Vol. 37, Pg. 1621, 1986.
mouse LD50 unreported 43mg/kg (43mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
rabbit LD50 oral 160mg/kg (160mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(2), Pg. 58, 1970.
rabbit LD50 skin 1160mg/kg (1160mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LC50 inhalation 1730mg/m3/4H (1730mg/m3)   Pesticide Manual. Vol. 9, Pg. 856, 1991.
rat LD50 oral 64mg/kg (64mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 233, 1976.
rat LD50 unreported 64mg/kg (64mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.

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Sol Chem Marketing & Research Co., Ltd.
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Hangzhou J&H Chemical Co., Ltd
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YiPeng Chemical
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Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China
HangZhou Peak Chemical Co.,Ltd
Tel:+86-571-88233073
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Fujian Sannong Group Co., Ltd.
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Address: Xubi Sanming Fujian,China

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