22832-87-7|Miconazole nitrateProducts Supply - Chemical intermediates Network

Miconazole nitrate cas no:22832-87-7

Synonyms: 1-(2,4-dichloro-beta-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole nitrate

Identification

NameMiconazole nitrate
CAS22832-87-7
Synonyms1-(2,4-dichloro-beta-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole nitrate
EINECS(EC#)245-256-6
Molecular FormulaC18H14Cl4N2O?HNO3
Molecular Weight479.15

Chemical Properties

AppearanceWhite crystal powder

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful
Risk R22;R43
Safety

Hazard Codes:? Harmful Xn
Risk Statements: 22-43-40?
R22:Harmful if swallowed.?
R43:May cause sensitization by skin contact.?
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 36/37?
S36/37:Wear suitable protective clothing and gloves.
RIDADR: 3249
WGK Germany :3
RTECS: NI4771000
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 160mg/kg (160mg/kg)	?	Chemotherapy Vol. 17(6), Pg. 392, 1972.
guinea pig	LD50	oral	276mg/kg (276mg/kg)	?	Chemotherapy Vol. 17(6), Pg. 392, 1972.
mouse	LD50	intraperitoneal	480mg/kg (480mg/kg)	?	Drugs in Japan Vol. 6, Pg. 809, 1982.
mouse	LD50	intravenous	28mg/kg (28mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 181, 1980.
mouse	LD50	oral	578mg/kg (578mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Chemotherapy Vol. 17(6), Pg. 392, 1972.
mouse	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 353, 1976.
rat	LD50	intraperitoneal	1060mg/kg (1060mg/kg)	?	Drugs in Japan Vol. 6, Pg. 809, 1982.
rat	LD50	intravenous	14700ug/kg (14.7mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 181, 1980.
rat	LD50	oral	920mg/kg (920mg/kg)	?	Drugs in Japan Vol. 6, Pg. 809, 1982.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 7, Pg. 353, 1976.

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Miconazole nitrate cas no:22832-87-7

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