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Aspartame cas no:22839-47-0

Synonyms: r-Sweet;(3S)-3-amino-3-[[(1S)-1-methoxycarbonyl-2-phenyl-ethyl]carbamoyl]propanoic acid;Sweet cornSweet dipeptide;(3S)-3-azaniumyl-3-[[(1S)-1-methoxycarbonyl-2-phenyl-ethyl]carbamoyl]propanoate;NutraSweet;H-Asp-Phe-OMe;3-amino-3-[(1-methoxycarbonyl-2-phenyl-ethyl)carbamoyl]propanoic acid;L-Phenylalanine,L-R-aspartyl-,2-methyl ester;Aspartame (USAN);Aspartame FCC 4;Succinamic acid, 3-amino-N-(alpha-carboxyphenethyl)-,N-methyl ester;Aspartame FCC4;Aspartame Granula;β-Aspartame;

Identification
NameAspartame
CAS22839-47-0
Synonymsr-Sweet;(3S)-3-amino-3-[[(1S)-1-methoxycarbonyl-2-phenyl-ethyl]carbamoyl]propanoic acid;Sweet cornSweet dipeptide;(3S)-3-azaniumyl-3-[[(1S)-1-methoxycarbonyl-2-phenyl-ethyl]carbamoyl]propanoate;NutraSweet;H-Asp-Phe-OMe;3-amino-3-[(1-methoxycarbonyl-2-phenyl-ethyl)carbamoyl]propanoic acid;L-Phenylalanine,L-R-aspartyl-,2-methyl ester;Aspartame (USAN);Aspartame FCC 4;Succinamic acid, 3-amino-N-(alpha-carboxyphenethyl)-,N-methyl ester;Aspartame FCC4;Aspartame Granula;β-Aspartame;
EINECS(EC#)245-261-3
Molecular FormulaC14H18N2O5
Molecular Weight294.31
Chemical Properties
AppearanceWhite powder or tablets
alpha15.5 o (C=4, 15N FORMIC ACID)
refractive index14.5 ° (C=4, 15mol/L Formic Acid)
storage temp2-8°C
Safety Data

Safety

Human systemic effects by ingestion: allergic dermatitis. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
Safety Statements?of Aspartame (CAS NO.22839-47-0): 22-24/25?
S22: Do not breathe dust.?
S24/25: Avoid contact with skin and eyes.
WGK Germany: 2


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg) ? Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
mouse LD50 oral > 10gm/kg (10000mg/kg) ? Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg) ? Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
rat LD50 oral > 10gm/kg (10000mg/kg) ? Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
women TDLo oral 3710ug/kg (3.71mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" Annals of Internal Medicine. Vol. 104, Pg. 207, 1986.

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