22862-76-6|3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)-Products Supply

3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)- cas no:22862-76-6

Synonyms: 3,4-Pyrrolidinediol,2-(p-methoxybenzyl)-, 3-acetate, (2R,3S,4S)- (8CI);3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, [2R-(2a,3a,4b)]-;Anisomycin (6CI,7CI);(-)-Anisomycin;(2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate;(2R,3S,4S)-2-(p-Methoxyphenylmethyl)-3-acetoxy-4-hydroxypyrrolidine;Anisomycin, (-)-;Flagecidin;NSC 76712;

Identification

Name3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)-
CAS22862-76-6
Synonyms3,4-Pyrrolidinediol,2-(p-methoxybenzyl)-, 3-acetate, (2R,3S,4S)- (8CI);3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, [2R-(2a,3a,4b)]-;Anisomycin (6CI,7CI);(-)-Anisomycin;(2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate;(2R,3S,4S)-2-(p-Methoxyphenylmethyl)-3-acetoxy-4-hydroxypyrrolidine;Anisomycin, (-)-;Flagecidin;NSC 76712;
EINECS(EC#)245-269-7
Molecular FormulaC₁₄H₁₉NO₄
Molecular Weight265.30496

Chemical Properties

AppearanceWhite crystalline solid
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard T: Toxic;
Risk R25
Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.

Hazard Codes: Toxic T Harmful Xn
Risk Statements: 25-36/37/38-20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R25 :Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 45-36-26
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD	oral	> 200mg/kg (200mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
dog	LD	intramuscular	> 100mg/kg (100mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
dog	LD	intravenous	> 100mg/kg (100mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
dog	LD	oral	> 300mg/kg (300mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
guinea pig	LDLo	oral	300mg/kg (300mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
monkey	LD	intramuscular	> 50mg/kg (50mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
monkey	LD	oral	> 300mg/kg (300mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
monkey	LDLo	intravenous	200mg/kg (200mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
mouse	LD50	intraperitoneal	400mg/kg (400mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
mouse	LD50	intravenous	10mg/kg (10mg/kg)		"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 5, Pg. 77, 1981.
mouse	LD50	oral	148mg/kg (148mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
mouse	LD50	subcutaneous	600mg/kg (600mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
rabbit	LD	oral	> 200mg/kg (200mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
rat	LD50	intraperitoneal	345mg/kg (345mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
rat	LD50	intravenous	167mg/kg (167mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
rat	LD50	oral	72mg/kg (72mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.
rat	LD50	subcutaneous	230mg/kg (230mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 490, 1955.

supplier list

LKT Laboratories, Inc.: Tel:+1-(651)-644-8357; Address: 2233 University Avenue West, St. Paul, Minnesota 55114-1629,

Fermentek Ltd: Tel:972 2 5853953; Address: Yatziv 25, POB 47120, Jerusalem 97800 Israel

BIOTREND Chemikalien GmbH: Tel:+49-221-9498320; Address: Eupener Str. 157, 50933 Cologne, Germany

CFM Oskar Tropitzsch: Tel:+49-(9231)-9619-0; Address: Oskar Tropitzsch, Gaderstrasse 1, Marktredwitz D-95615,

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road, Shirley, NY 11967, USA

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd: Tel:86-571-85335020; Address: 1018 Guangyin Building,No.42 E.Fengqi Road,Hangzhou,310012 China.

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

Chem-Impex International Inc.: Tel:+1-(630)-766-2112; Address: Corporate Office:, 935 N. Dillon Drive, Wood Dale, Illinois 60191,

3,4-Pyrrolidinediol,2-[(4-methoxyphenyl)methyl]-, 3-acetate, (2R,3S,4S)- cas no:22862-76-6

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