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Silymarin cas no:22888-70-6

Synonyms: 4H-1-Benzopyran-4-one,2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;4-Chromanone,3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-(8CI);4H-1-Benzopyran-4-one,2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,[2R-[2a,3b,6(2R*,3R*)]]-;Silybin (7CI);1,4-Benzodioxin,4H-1-benzopyran-4-one deriv.;7C3MT;Silibinin;Silliver;Silybin A;Silybinb1;Silybine;Silybum substance E6;Silymarin I;Silymarin MZ 80;Silymarine I;Milk thistle P.E(Silibinin);Silymarine;

Identification
NameSilymarin
CAS22888-70-6
Synonyms4H-1-Benzopyran-4-one,2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,(2R,3R)-;4-Chromanone,3,5,7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxan-6-yl]-(8CI);4H-1-Benzopyran-4-one,2-[2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-,[2R-[2a,3b,6(2R*,3R*)]]-;Silybin (7CI);1,4-Benzodioxin,4H-1-benzopyran-4-one deriv.;7C3MT;Silibinin;Silliver;Silybin A;Silybinb1;Silybine;Silybum substance E6;Silymarin I;Silymarin MZ 80;Silymarine I;Milk thistle P.E(Silibinin);Silymarine;
EINECS(EC#)245-302-5
Molecular FormulaC25H22 O10
Molecular Weight482.43618
Chemical Properties
Appearancesolid
storage temp?20°C
Safety Data

Hazard Xi
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39-24/25-22-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S37/39:Wear suitable gloves and eye/face protection.?
S24/25:Avoid contact with skin and eyes.?
S22:Do not breathe dust.?
S36:Wear suitable protective clothing.
RIDADR: 3172
WGK Germany: 3
RTECS: DJ2981770


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 1056mg/kg (1056mg/kg) ? Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 404, 1983.
rabbit LDLo unreported 300mg/kg (300mg/kg) ? Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 404, 1983.

supplier list

Genatal Life Science Ltd.
Tel:+86-(21)-54302195
Address: No.258, South HeHua Road, Shanghai,
Ningbo Victory & Prosperity Chemistry CO.,LTD.
Tel:+86-(574)-27666767
Address: 21/F, No.11 Bldg, Xin Tian Di, NO 689, Shi Ji Road, NINGBO 315040,
Xi'an App Chem-Bio(Tech) Co., Ltd.
Tel:+86-(29)-88327527
Address: 6F, Building C, R&D park, No.69 Jingye Rd.1 , High tech Zone, Xi'an 710076,
Shaanxi Jiahe Phytochem Co., Ltd.
Tel:+86-(29)-88326710
Address: 37 Keji Road, Suite B2704 Seastar City Plaza, Xi'an, Shaanxi 710075,
Panjin Hengchanglong Refined Chemical Co., Ltd.
Tel:+86-(427)-3209909
Address: RM 308 Office Building, Development Zone, Panjin, Liaoning,
DaXingAnLing Virgin Forest Plant Products Co., Ltd.(info3 at virginforestplant dot com)
Tel:86-452-6188052
Address: 118 YongXin Road, SongLing District, DaXingAnLing City, HeiLongJiang, China
Kailu Ever Brilliance Biotechnology Co., Ltd.
Tel:+86-(512)-87103711
Address: 1-919, Bldg 8, East block, Donghuashi Nanli, Chongwen District, Beijing 100062,
Hangzhou Shenying Medicine Chemical Co.,Ltd
Tel:86-571-82106688
Address: Jiangdong development Zone in Xinwan town, Xiaoshan
HBCChem, Inc.
Tel:+1-510-219-6317
Address:
Nanjing Kinglion Pharmachem. Co., Ltd.
Tel:+86-25-83585046
Address: No.118 Tangquan Industrial development Zone, Pukou , Nanjing, P.R.China
Pingyin Jincheng Chemical Plant
Tel:0531-87687111
Address: Meigui town,Pinyin County,Jinan City
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Tel:18721563304
Address: Pudong District Janyun road 500th
Xi'an Biosunny Biological Technology Co.,Ltd.
Tel:+86-29-8773 1281
Address: Address:11-4, Dongxing building ,No.9 Jiangong Xi'an,China
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Tel:86-27-59335372
Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Nutra-Y Co.,Ltd
Tel:86-731-89352076
Address: Gaoqiao Business District

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