4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, hydrochloride (1:1) cas no:23076-35-9
Synonyms: 4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride (9CI);4H-1,3-Thiazine,5,6-dihydro-2-(2,6-xylidino)-, monohydrochloride (8CI);5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride;BAY 1470hydrochloride;BAY-Va 1470;Celactal;Narcosyl;Rompun;Xylapan;Xylasol;Xylazine chloride;Xylazine hydrochloride;? Xylazine hydrochloride;
Name4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, hydrochloride (1:1)
CAS23076-35-9
Synonyms4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro-, monohydrochloride (9CI);4H-1,3-Thiazine,5,6-dihydro-2-(2,6-xylidino)-, monohydrochloride (8CI);5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride;BAY 1470hydrochloride;BAY-Va 1470;Celactal;Narcosyl;Rompun;Xylapan;Xylasol;Xylazine chloride;Xylazine hydrochloride;? Xylazine hydrochloride;
EINECS(EC#)245-417-0
Molecular FormulaC12H16N2S.HCl
Molecular Weight256.79
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard T: Toxic;
Risk R25;R36/37/38
Safety
Hazard Codes: 
T
Risk Statements: 25-36/37/38
R25 :Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39-45
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 2811
RTECS: XJ0776350
HazardClass: 6.1(b)
PackingGroup: III
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
intramuscular |
47mg/kg (47mg/kg) |
|
Clinical Toxicology. Vol. 15, Pg. 281, 1979. |
| guinea pig |
LD50 |
intramuscular |
10mg/kg (10mg/kg) |
|
Veterinary and Human Toxicology. Vol. 24, Pg. 410, 1982. |
| man |
TDLo |
intramuscular |
14mg/kg (14mg/kg) |
BEHAVIORAL: COMA
CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Clinical Toxicology. Vol. 15, Pg. 281, 1979. |
| mouse |
LD50 |
intramuscular |
109mg/kg (109mg/kg) |
|
Zhongguo Yaolixue Yu Dulixue Zazhi. Vol. 9, Pg. 96, 1995. |
| mouse |
TDLo |
subcutaneous |
29uL/kg (0.029mL/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Postgraduate Medical Journal. Vol. 66, Pg. 244, 1990. |
| rat |
LDLo |
oral |
150mg/kg (150mg/kg) |
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BLOOD: OTHER CHANGES |
Journal of Toxicological Sciences. Vol. 25, Pg. 105, 2000. |
