1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (1R)- cas no:23107-12-2

Synonyms: 1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (R)-; Retronecine, 3,8-didehydro- (8CI); Dehydroretronecine;Retronecine pyrrole

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

Name1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (1R)-
CAS23107-12-2
Synonyms1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (R)-; Retronecine, 3,8-didehydro- (8CI); Dehydroretronecine;Retronecine pyrrole
Molecular FormulaC8H11 N O2
Molecular Weight153.20

Chemical Properties

refractive index1.65

Safety Data

Safety

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	mmo-sat 500 µg/plate	MUREAV Mutation Research. 149 (1985),485.
2.	sce-hmn:lym 1 µmol/L	MUREAV Mutation Research. 149 (1985),485.
3.	dni-rat:lvr 100 µmol/L	CBINA8 Chemico-Biological Interactions. 30 (1980),325.
4.	oms-rat:lvr 20 µmol/L	CBINA8 Chemico-Biological Interactions. 30 (1980),325.
5.	otr-ham:kdy 250 µg/L	CRNGDP Carcinogenesis. 1 (1980),161.
6.	ipr-rat LD50:122 mg/kg	CBINA8 Chemico-Biological Interactions. 12 (1976),299.

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