3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-, 3,5-diethylester cas no:23191-75-5

Synonyms: 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(a,a,a-trifluoro-o-tolyl)-, diethyl ester (8CI);3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-, diethyl ester (9CI);1,4-Dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylicacid diethyl ester;3,5-Dicarbethoxy-2,6-dimethyl-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine;4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine;Ftorin; Ftorin (pharmaceutical); SKF 24260

Identification

Name3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-, 3,5-diethylester
CAS23191-75-5
Synonyms3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(a,a,a-trifluoro-o-tolyl)-, diethyl ester (8CI);3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]-, diethyl ester (9CI);1,4-Dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylicacid diethyl ester;3,5-Dicarbethoxy-2,6-dimethyl-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine;4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine;Ftorin; Ftorin (pharmaceutical); SKF 24260
Molecular FormulaC20H22 F3 N O4
Molecular Weight397.43

Chemical Properties

refractive index1.496

Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of F⁻ and NO_x.
Risk Statements: 37
R37: Irritating to respiratory system
RTECS: ZH5200000

Toxicity

1.	orl-rat LD50:1225 mg/kg	JMCMAR Journal of Medicinal Chemistry. 17 (1974),956.
2.	ivn-rat LDLo:5 mg/kg	JMCMAR Journal of Medicinal Chemistry. 17 (1974),956.
3.	orl-mus LD50:1480 mg/kg	JMCMAR Journal of Medicinal Chemistry. 17 (1974),956.
4.	ipr-mus LD50:38 mg/kg	PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 16 (1982),817.
5.	ivn-dog LDLo:700 µg/kg	JMCMAR Journal of Medicinal Chemistry. 17 (1974),956.

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