2321-07-5|Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-dihydroxy-Products Supply

Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-dihydroxy- cas no:2321-07-5

Synonyms: Fluorescein(8CI);3,6-Dihydroxyspiro[xanthene-9,3'-phthalide];3',6'-Fluorandiol;Benzoic acid,2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-;C.I. 45350:1;D and C Yellow No. 7;3',6'-Dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one;C Yellow No. 7;Japan Yellow 201;Japan Yellow No. 201;Resorcinolphthalein;Yellow fluorescein;

Identification

NameSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-dihydroxy-
CAS2321-07-5
SynonymsFluorescein(8CI);3,6-Dihydroxyspiro[xanthene-9,3'-phthalide];3',6'-Fluorandiol;Benzoic acid,2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-;C.I. 45350:1;D and C Yellow No. 7;3',6'-Dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one;C Yellow No. 7;Japan Yellow 201;Japan Yellow No. 201;Resorcinolphthalein;Yellow fluorescein;
EINECS(EC#)219-031-8
Molecular FormulaC₂₀H₁₂O₅
Molecular Weight332.31

Chemical Properties

Appearanceorange-red crystalline powder
refractive index1.46355
storage temp−20°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard Xi:Irritant;
Risk R36;R43
Safety

Hazard Codes of Fluorescein (CAS NO.2321-07-5): Irritant Xi
Risk Statements: 43-36/37/38
R43: May cause sensitization by skin contact.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-26-36/37/39-27
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S27: Take off immediately all contaminated clothing.
WGK Germany: 3
RTECS: LM5075000
F: 10-21
Poison by intravenous route. Moderately toxic by intraperitoneal route. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also FLUORESCEIN SODIUM.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	unreported	400mg/kg (400mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
man	TDLo	intravenous	7143nL/kg (7143mL/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	American Journal of Ophthalmology. Vol. 126, Pg. 837, 1998.
mouse	LD50	intravenous	300mg/kg (300mg/kg)		United States Patent Document. Vol. #4775625,
mouse	LDLo	unreported	600mg/kg (600mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rabbit	LDLo	intravenous	300mg/kg (300mg/kg)		International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934.
rat	LDLo	intraperitoneal	600mg/kg (600mg/kg)		International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934.

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Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,3',6'-dihydroxy- cas no:2321-07-5

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