5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-,(8S,10S)- cas no:23214-92-8
Synonyms: 5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,(8S,10S)- (9CI);14-Hydroxydaunomycin;63: PN: WO2010011890 PAGE: 37 claimedsequence;Biotransdox;Caelyx;Doxil;Doxorubicin;Evacet;Hydroxydaunomycin;NSC 123127;PK 2;Rubex;
Name5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-,(8S,10S)-
CAS23214-92-8
Synonyms5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,(8S,10S)- (9CI);14-Hydroxydaunomycin;63: PN: WO2010011890 PAGE: 37 claimedsequence;Biotransdox;Caelyx;Doxil;Doxorubicin;Evacet;Hydroxydaunomycin;NSC 123127;PK 2;Rubex;
EINECS(EC#)245-495-6
Molecular FormulaC27H29NO11
Molecular Weight543.52
Appearanceorange to red powder
refractive index1.709
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Hazard UN
NO.
Safety Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal, subcutaneous, parenteral, and intravenous routes. Human systemic effects by intravenous route: cardiac myopathy including infarction, nausea or vomiting, and effects on the hair. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
