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HYCANTHONE METHANESULFONATE cas no:23255-93-8

Synonyms: N-[2-(diethylamino)ethyl]-4-methoxy-9-oxoxanthene-1-amine monomethanesulphonate;HYCANTHONEMETHANESULPHONATE;HYCANTHONEMESYLATE

Identification
NameHYCANTHONE METHANESULFONATE
CAS23255-93-8
SynonymsN-[2-(diethylamino)ethyl]-4-methoxy-9-oxoxanthene-1-amine monomethanesulphonate;HYCANTHONEMETHANESULPHONATE;HYCANTHONEMESYLATE
EINECS(EC#)245-527-9
Molecular FormulaC20H24N2O2S . CH4O3S
Molecular Weight452.58742
Chemical Properties
Appearanceyellow to orange powder
Safety Data

Safety

A poison by intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Other experimental reproductive effects. Human systemic effects by intramuscular route: hallucinations, muscle weakness, nausea or vomiting. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx. See also SULFONATES.


Toxicity
1.    

dnr-esc 16 µg/well

    ENMUDM    Environmental Mutagenesis. 3 (1981),429.
2.    

cyt-hmn:leu 1 µmol/L

    MUREAV    Mutation Research. 21 (1973),287.
3.    

cyt-hmn:lym 2400 µg/L

    JTEHD6    Journal of Toxicology and Environmental Health. 1 (1976),211.
4.    

dni-hmn:lym 50 mg/L

    BCPCA6    Biochemical Pharmacology. 22 (1973),1253.
5.    

sln-dmg-par 4400 µmol/L

    MUREAV    Mutation Research. 82 (1981),111.
6.    

sln-dmg-orl 4400 µmol/L

    MUREAV    Mutation Research. 82 (1981),111.
7.    

otr-rat-ipr 30 mg/kg

    CNREA8    Cancer Research. 40 (1980),1157.
8.    

ipr-mus TDLo:815 mg/kg/33W-I:CAR

    IJCNAW    International Journal of Cancer. 23 (1979),97.
9.    

ims-hmn TDLo:3 mg/kg:CNS,GIT

    PACHAS    Pure and Applied Chemistry. 42 (1975),209.
10.    

ipr-rat LDLo:100 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 187 (1973),437.
11.    

orl-mus LD50:565 mg/kg

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