4-Thiomorpholinamine,3-methyl-N-[(5-nitro-2-furanyl)methylene]-, 1,1-dioxide cas no:23256-30-6

Name4-Thiomorpholinamine,3-methyl-N-[(5-nitro-2-furanyl)methylene]-, 1,1-dioxide
CAS23256-30-6
SynonymsThiomorpholine,3-methyl-4-[(5-nitrofurfurylidene)amino]-, 1,1-dioxide (7CI,8CI); (?à)-Nifurtimox;3-Methyl-4-(5-nitrofurfurylideneamino)tetrahydro-1,4-thiazine-1,1-dioxide;4-(5-Nitrofurfurylideneamino)-3-methylthiomorpholine 1,1-dioxide; BAY 2502;Bayer 2502; Lampit; Nifurtimox;Tetrahydro-3-methyl-4-[(5-nitrofurfurylidene)amino]-4H-1,4-thiazine 1,1-dioxide
EINECS(EC#)245-531-0
Molecular FormulaC10H13 N3 O5 S
Molecular Weight287.32

refractive index1.653

Safety

Moderately toxic by ingestion. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic and teratogenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and SO_x. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.

1.		mmo-esc 50 mg/L		MUREAV    Mutation Research. 77 (1980),241.
2.		dnr-esc 500 mg/L		FOMIAZ    Folia Microbiologica (Prague). (Academia, Vodickova 40, CS-112 29 Prague 1, 25 (1980),388.
3.		dnd-omi 100 µmol/L		BCPCA6    Biochemical Pharmacology. 34 (1984),1457.
4.		mnt-mus-orl 600 mg/kg		TOLED5    Toxicology Letters. 25 (1985),259.
5.		orl-rat LD50:4050 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 22 (1972),1590.
6.		orl-mus LD50:2291 mg/kg		TRSTAZ    Transactions of the Royal Society of Tropical Medicine and Hygiene. 74 (1980),43.
7.		orl-rbt LD50:2 g/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 22 (1972),1590.