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GUANABENZ ACETATE cas no:23256-50-0

Synonyms: ((2,6-dichlorobenzylidene)amino)-guanidinmonoacetate;2-((2,6-dichlorophenyl)methylene)-hydrazinecarboximidamidmonoacetate;br750;WY-8678;[2,6-DICHLOROBENZYLIDENE)-AMINO]GUANIDINE;[(2,6-DICHLOROBENZYLIDENE)AMINO]GUANIDINE ACETATE;GUANABENZ ACETATE;3-[(2,6-dichlorophenyl)methylene]carbazamidine monoacetate

Identification
NameGUANABENZ ACETATE
CAS23256-50-0
Synonyms((2,6-dichlorobenzylidene)amino)-guanidinmonoacetate;2-((2,6-dichlorophenyl)methylene)-hydrazinecarboximidamidmonoacetate;br750;WY-8678;[2,6-DICHLOROBENZYLIDENE)-AMINO]GUANIDINE;[(2,6-DICHLOROBENZYLIDENE)AMINO]GUANIDINE ACETATE;GUANABENZ ACETATE;3-[(2,6-dichlorophenyl)methylene]carbazamidine monoacetate
EINECS(EC#)245-534-7
Molecular FormulaC8H8Cl2N4•C2H4O2
Molecular Weight231.08192
Chemical Properties
Appearancewhite solid
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Poison by ingestion, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: sleep, pulse rate and blood pressure changes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl and NOx. A hypotensive drug.
Safety Information about Acetic acid; 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine (CAS NO.23256-50-0):
Hazard Codes: 
Xn:
Risk Statements about Acetic acid; 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine (CAS NO.23256-50-0):
R22:
Safety Statements about Acetic acid; 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine (CAS NO.23256-50-0):
S22: Harmful if swallowed.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: MF0382000
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

orl-chd TDLo:1 mg/kg:CNS,CVS

    AIMEAS    Annals of Internal Medicine. 102 (1985),787.
2.    

orl-wmn TDLo:1 mg/kg:CNS,CVS

    AIMEAS    Annals of Internal Medicine. 102 (1985),787.
3.    

orl-rat LD50:238 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.
4.    

ipr-rat LD50:62 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.
5.    

scu-rat LD50:84 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.
6.    

orl-mus LD50:260 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.
7.    

ipr-mus LD50:75 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.
8.    

scu-mus LD50:89 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 10 (1982),4571.

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