6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride cas no:2328-12-3
Synonyms: Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (7CI,8CI,9CI);1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinolinehydrochloride;6,7-Bis(methyloxy)-1,2,3,4-tetrahydroisoquinoline hydrochloride;Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1);6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline monohydrochloride;6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinehydrochloride;Heliamine hydrochloride;
Name6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS2328-12-3
SynonymsIsoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (7CI,8CI,9CI);1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinolinehydrochloride;6,7-Bis(methyloxy)-1,2,3,4-tetrahydroisoquinoline hydrochloride;Isoquinoline,1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1);6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline monohydrochloride;6,7-Dimethoxy-3,4-dihydro-2(1H)-isoquinolinehydrochloride;Heliamine hydrochloride;
EINECS(EC#)251-223-7
Molecular FormulaC11H16ClNO2
Molecular Weight229.7
Appearancewhite to slightly beige shiny flakes
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Hazard Xi:Irritant;
Risk R36/37/38
Safety
Hazard Codes: 
Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: NX5017980
Hazard Note: Irritant
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
272mg/kg (272mg/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Yakugaku Zasshi. Journal of Pharmacy. Vol. 88, Pg. 1197, 1968.
|
| mouse |
LDLo |
parenteral |
160mg/kg (160mg/kg) |
BEHAVIORAL: TREMOR
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 165, 1938. |
