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Home > products > 1H-2,5-Benzoxazocine,3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1)

1H-2,5-Benzoxazocine,3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1) cas no:23327-57-3

Synonyms: 1H-2,5-Benzoxazocine,3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (8CI,9CI);Acupan;Ajan;Fenazoxine hydrochloride;R 738;

Identification
Name1H-2,5-Benzoxazocine,3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (1:1)
CAS23327-57-3
Synonyms1H-2,5-Benzoxazocine,3,4,5,6-tetrahydro-5-methyl-1-phenyl-, hydrochloride (8CI,9CI);Acupan;Ajan;Fenazoxine hydrochloride;R 738;
EINECS(EC#)245-585-5
Molecular FormulaC17H19NO.HCl
Molecular Weight289.8
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

Poison by ingestion, intravenous, intraperitoneal, and intramuscular routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intramuscular 30mg/kg (30mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.
dog LD50 intravenous 20mg/kg (20mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.
dog LD50 oral 200mg/kg (200mg/kg)
behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea
Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.
mouse LD50 intramuscular 53mg/kg (53mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.
mouse LD50 intraperitoneal 70mg/kg (70mg/kg) ? "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 269, 1972.
mouse LD50 intravenous 45mg/kg (45mg/kg) ? "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 269, 1972.
mouse LD50 oral 119mg/kg (119mg/kg) ? "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 269, 1972.
rat LD50 intramuscular 57mg/kg (57mg/kg)
behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea
Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.
rat LD50 intravenous 28mg/kg (28mg/kg) ? "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 269, 1972.
rat LD50 oral 80mg/kg (80mg/kg)
behavioral: convulsions or effect on seizure threshold behavioral: excitement lungs, thorax, or respiration: dyspnea
Toxicology and Applied Pharmacology. Vol. 33, Pg. 46, 1975.

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