Phenol,4-[6-(4-methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]-, hydrochloride(1:3) cas no:23491-45-4

NamePhenol,4-[6-(4-methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]-, hydrochloride(1:3)
CAS23491-45-4
SynonymsPhenol,4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-,trihydrochloride (9CI); Phenol,p-[5-[5-(4-methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]-,trihydrochloride (8CI);2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazinyl)benzimidazoletrihydrochloride; 2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)-benzimidazoletrihydrochloride;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)benzimidazoletrichloride;2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)benzimidazole-3HCl;2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole;4-[5-[5-(4-Methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]phenoltrihydrochloride; Bisbenzimide; Bisbenzimide (quenchant); Bisbenzimidetrihydrochloride; H 33258; HOE 33258; Ho 33258; Hoechst 33258; NSC 322921;Pibenzimol hydrochloride
EINECS(EC#)245-690-6
Molecular FormulaC25H24 N6 O . 3 Cl H
Molecular Weight533.93

Appearanceyellow-green powder.
storage temp2-8°C

Hazard Xn: Harmful;
Risk R22
Safety

Poison by intravenous route. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NO_x.
Safety Information about  4-[5-[6-(4-Methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,3-dihydrobenzimidazol-2-ylidene]cyclohexa-2,5-dien-1-one trihydrochloride (CAS NO.23491-45-4 ):
Hazard Codes: 
Xn:
Risk Statements about  4-[5-[6-(4-Methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,3-dihydrobenzimidazol-2-ylidene]cyclohexa-2,5-dien-1-one trihydrochloride (CAS NO.23491-45-4 ): R22: Harmful if swallowed.
R36/38: Irritating to eyes and skin.
R36/37/38: Irritating to eyes, respiratory system and skin.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements about  4-[5-[6-(4-Methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,3-dihydrobenzimidazol-2-ylidene]cyclohexa-2,5-dien-1-one trihydrochloride (CAS NO.23491-45-4 ) S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S24/25: Avoid contact with skin and eyes.
S23: Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer).
F3: Hygroscopic.
F8: Photosensitive.
F10: Keep under argon.
WGK Germany: 3
RTECS: SM1140500

1.		mmo-sat 100 µmol/L		AMACCQ    Antimicrobial Agents and Chemotherapy. 9 (1976),77.
2.		dnd-esc 10 mg/L		MUREAV    Mutation Research. 89 (1981),95.
3.		sce-ham:lng 15 µmol/L		HEREAY    Hereditas. 96 (1982),295.
4.		sce-ham:ovr 10 µmol/L		NATUAS    Nature. 258 (1975),121.
5.		ivn-rat LD50:32,200 µg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB84-171206 .
6.		ivn-mus LD50:36,900 µg/kg		NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB84-171206 .