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Thiophanate ethyl ([1,2-Phenylenebis (iminocarbonothioyl)] biscarbamic acid diethyl ester) cas no:23564-06-9

Synonyms: Allophanicacid, 4,4'-o-phenylenebis[3-thio-, diethyl ester (8CI); Carbamic acid,[1,2-phenylenebis(iminocarbonothioyl)]bis-, diethyl ester (9CI);1,2-Bis(3-ethoxycarbonyl-2-thioureido)benzene;1,2-Bis[3-(ethoxycarbonyl)thioureido]benzene; BAS 3220; Cercobin; Enovit; Ethylthiophanate; NBF 35; NF 35; NF 35 (fungicide); NSC 170810; Pelt; Pelt(pesticide); Quali-Pro TM 85WDG; Systec 1998WDG; Thiofanate; Thiophanat;Thiophanate; Thiophanate ethyl; Topsin; Topsin E; Topsin NF 35

Identification
NameThiophanate ethyl ([1,2-Phenylenebis (iminocarbonothioyl)] biscarbamic acid diethyl ester)
CAS23564-06-9
SynonymsAllophanicacid, 4,4'-o-phenylenebis[3-thio-, diethyl ester (8CI); Carbamic acid,[1,2-phenylenebis(iminocarbonothioyl)]bis-, diethyl ester (9CI);1,2-Bis(3-ethoxycarbonyl-2-thioureido)benzene;1,2-Bis[3-(ethoxycarbonyl)thioureido]benzene; BAS 3220; Cercobin; Enovit; Ethylthiophanate; NBF 35; NF 35; NF 35 (fungicide); NSC 170810; Pelt; Pelt(pesticide); Quali-Pro TM 85WDG; Systec 1998WDG; Thiofanate; Thiophanat;Thiophanate; Thiophanate ethyl; Topsin; Topsin E; Topsin NF 35
EINECS(EC#)245-741-2
Molecular FormulaC14H18 N4 O4 S2
Molecular Weight370.48
Chemical Properties
refractive index1.676
storage temp0-6°C
Safety Data

Safety

Moderately toxic by intraperitoneal route. Experimental reproductive effects. Mutation data reported. A fungicide. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also CARBAMATES.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LDLo oral 2gm/kg (2000mg/kg)   British Veterinary Journal. Vol. 130, Pg. 570, 1974.
guinea pig LD50 oral > 10gm/kg (10000mg/kg)   Japan Pesticide Information. Vol. (7), Pg. 27, 1971.
guinea pig LD50 skin > 10gm/kg (10000mg/kg)   Japan Pesticide Information. Vol. (1), Pg. 26, 1969.
mouse LD50 intraperitoneal 3750mg/kg (3750mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 5, 1970.
mouse LD50 oral > 15gm/kg (15000mg/kg)   Japan Pesticide Information. Vol. (7), Pg. 27, 1971.
mouse LD50 skin > 15gm/kg (15000mg/kg)   Japan Pesticide Information. Vol. (1), Pg. 26, 1969.
rabbit LD50 oral > 10gm/kg (10000mg/kg)   Japan Pesticide Information. Vol. (7), Pg. 27, 1971.
rabbit LD50 skin > 10gm/kg (10000mg/kg)   Japan Pesticide Information. Vol. (1), Pg. 26, 1969.
rat LD50 intraperitoneal 2400mg/kg (2400mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 4, Pg. 5, 1970.
rat LD50 oral > 15gm/kg (15000mg/kg)   Japan Pesticide Information. Vol. (7), Pg. 27, 1971.
rat LD50 skin > 15gm/kg (15000mg/kg)   Japan Pesticide Information. Vol. (1), Pg. 26, 1969.

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