23593-75-1|ClotrimazoleProducts Supply - Chemical intermediates Network

Clotrimazole cas no:23593-75-1

Synonyms: Diphenyl(2-chlorophenyl)(1-imidazolyl)methane;Bay-B 5097;BAYb 5097;Mycelex (TN);(2-Chlorophenyl)diphenyl-1-imidazolylmethane;Lotrimin (TN);Clotrimazol [INN-Spanish];Gyne-Lotrimin;1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole;Mycelex Troches;1H-Imidazole, 1-[ (2-chlorophenyl)diphenylmethyl]-;Imidazole, 1- (o-chloro-.alpha.,.alpha.-diphenylbenzyl)-;Bis-fenil-(2-clorofenil)-1-imidazolil-metano [Italian];Lotrimin AF Cream;1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole;Lotrimax;Prestwick_120;FB 5097;Monobaycuten;1-(o-Chloro-.alpha., .alpha.-diphenylbenzyl)imidazole;Trimysten;Bis-phenyl-(2-chlorophenyl)-1-imidazoyl)methane;BAY b5097;Mykosporin;Mycelex G;

Identification

NameClotrimazole
CAS23593-75-1
SynonymsDiphenyl(2-chlorophenyl)(1-imidazolyl)methane;Bay-B 5097;BAYb 5097;Mycelex (TN);(2-Chlorophenyl)diphenyl-1-imidazolylmethane;Lotrimin (TN);Clotrimazol [INN-Spanish];Gyne-Lotrimin;1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole;Mycelex Troches;1H-Imidazole, 1-[ (2-chlorophenyl)diphenylmethyl]-;Imidazole, 1- (o-chloro-.alpha.,.alpha.-diphenylbenzyl)-;Bis-fenil-(2-clorofenil)-1-imidazolil-metano [Italian];Lotrimin AF Cream;1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole;Lotrimax;Prestwick_120;FB 5097;Monobaycuten;1-(o-Chloro-.alpha., .alpha.-diphenylbenzyl)imidazole;Trimysten;Bis-phenyl-(2-chlorophenyl)-1-imidazoyl)methane;BAY b5097;Mykosporin;Mycelex G;
EINECS(EC#)245-764-8
Molecular FormulaC₂₂H₁₇ClN₂
Molecular Weight344.84

Chemical Properties

AppearanceCrystals. Odorless.
refractive index1.616
storage tempStore at RT.

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Safety Information of?Mycosporin (CAS NO.23593-75-1):
Hazard Codes:Xn?
Risk Statements:22-36/38
22:Harmful if swallowed
36/38:Irritating to eyes and skin??
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:Wear suitable protective clothing?
WGK Germany:3
RTECS:NI4377000
Hazardous Substances Data:23593-75-1(Hazardous Substances Data)
Poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. Human systemic effects by intrvaginal route: primary skin irritations. Experimental reproductive effects. A fungicide. When heated to decomposition it emits very toxic fumes of Cl^? and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	> 1gm/kg (1000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1272, 1972.
dog	LD50	oral	> 2gm/kg (2000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1272, 1972.
mammal (species unspecified)	LD50	oral	750mg/kg (750mg/kg)	?	Antimicrobial Agents and Chemotherapy Vol. -, Pg. 271, 1969.
mouse	LD50	intraperitoneal	108mg/kg (108mg/kg)	?	Drug and Chemical Toxicology. Vol. 13, Pg. 195, 1990.
mouse	LD50	intravenous	198mg/kg (198mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
mouse	LD50	oral	761mg/kg (761mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1272, 1972.
mouse	LDLo	subcutaneous	10gm/kg (10000mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1333, 1973.
rabbit	LD50	oral	> 1gm/kg (1000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1272, 1972.
rat	LD50	intraperitoneal	445mg/kg (445mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1333, 1973.
rat	LD50	oral	708mg/kg (708mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 22, Pg. 1272, 1972.
rat	LDLo	subcutaneous	10gm/kg (10000mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1333, 1973.
women	TDLo	intravaginal	28mg/kg/7D (28mg/kg)	SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE	Clinical Toxicology. Vol. 18, Pg. 41, 1981.

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Clotrimazole cas no:23593-75-1

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