23696-28-8|2-Quinoxalinecarboxamide,N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxideProducts Supply

2-Quinoxalinecarboxamide,N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide cas no:23696-28-8

Synonyms: 2-(N-(2-Hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid;N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide;BRN 0758489;

Identification

Name2-Quinoxalinecarboxamide,N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide
CAS23696-28-8
Synonyms2-(N-(2-Hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid;N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide;BRN 0758489;
EINECS(EC#)245-832-7
Molecular FormulaC₁₂H₁₃N₃O₄
Molecular Weight263.24932

Chemical Properties

AppearanceLight yellow crystalline powder,Odorless
refractive index1.65
storage temp0-6°C

Safety Data

Hazard Xn:Harmful;
Risk R22;R43

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD1582000

CHEMICAL NAME :: 2-Quinoxalinecarboxamide, N-(2-hydroxyethyl)-3-methyl-, 1,4-dioxide

CAS REGISTRY NUMBER :: 23696-28-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C12-H13-N3-O4

MOLECULAR WEIGHT :: 263.28

WISWESSER LINE NOTATION :: T66 BN ENJ BO CVM2Q D1 EO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1717 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4550 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 20 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 139,199,1984

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