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Acetic acid,2-isothiocyanato-, ethyl ester cas no:24066-82-8

Synonyms: Aceticacid, isothiocyanato-, ethyl ester (6CI,7CI,8CI,9CI); Carbethoxymethylisothiocyanate; Carboethoxymethyl isothiocyanate; Ethoxycarbonylmethylisothiocyanate; Ethyl isothiocyanatoacetate; Isothiocyanatoacetic acid ethylester

Identification
NameAcetic acid,2-isothiocyanato-, ethyl ester
CAS24066-82-8
SynonymsAceticacid, isothiocyanato-, ethyl ester (6CI,7CI,8CI,9CI); Carbethoxymethylisothiocyanate; Carboethoxymethyl isothiocyanate; Ethoxycarbonylmethylisothiocyanate; Ethyl isothiocyanatoacetate; Isothiocyanatoacetic acid ethylester
EINECS(EC#)417-720-1
Molecular FormulaC5H7 N O2 S
Molecular Weight145.18
Chemical Properties
refractive index1.502
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22;R36/37/38
Safety

A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx.

Hazard Codes: HarmfulXn
Risk Statements :20/21/22-36/37/38
R20/21/22: Ethyl isothiocyanoacetate (CAS NO.24066-82-8) is harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements :26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2810 6.1/PG 2
WGK: Germany 3
RTECS: AI5020000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LDLo subcutaneous 350mg/kg (350mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 35, Pg. 314, 1929

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Zhejiang Shou & Fu Chemical Co., Ltd.
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