24169-02-6|Econazole nitrateProducts Supply - Chemical intermediates Network

Econazole nitrate cas no:24169-02-6

Synonyms: (+-)-Econazole nitrate;1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate;1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate;

Identification

NameEconazole nitrate
CAS24169-02-6
Synonyms(+-)-Econazole nitrate;1-(2,4-Dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate;1-(2-((4-Chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate;
EINECS(EC#)246-053-5
Molecular FormulaC₁₈H₁₆Cl₃N₃O₄
Molecular Weight444.70

Chemical Properties

AppearanceWhite crystalline powder.
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Hazard Xn: Harmful;Xn: Harmful;Xi: Irritant;
Risk R22;R36/38
Safety

The Hazard Codes of Econazole nitrate (CAS NO.24169-02-6): ?Xn, Irritant Xi
Risk Statements:
22:? Harmful if swallowed?
36/37/38:? Irritating to eyes, respiratory system and skin?
36/38:? Irritating to eyes and skin?
Safety Statements:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
36/37:? Wear suitable protective clothing and gloves?
WGK Germany: 3
RTECS: NI4450000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 160mg/kg (160mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
guinea pig	LD50	oral	272mg/kg (272mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
mouse	LD50	intraperitoneal	180mg/kg (180mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
mouse	LD50	intravenous	38mg/kg (38mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
mouse	LD50	oral	463mg/kg (463mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
mouse	LD50	subcutaneous	750mg/kg (750mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rabbit	LD50	intravenous	85mg/kg (85mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rabbit	LD50	oral	431mg/kg (431mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1253, 1981.
rabbit	LD50	subcutaneous	650mg/kg (650mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	intraperitoneal	240mg/kg (240mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.
rat	LD50	oral	668mg/kg (668mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 224, 1975.
rat	LD50	subcutaneous	1360mg/kg (1360mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 643, 1978.

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Econazole nitrate cas no:24169-02-6

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