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Dexchloropheniramine maleate cas no:2438-32-6

Synonyms: Dexchlorpheniramine Maleate BP/USP;(+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate (1:1);D-Chlorpheniramine maleate;Polaramine (TN);(+)-Chlorpheniramine maleate;Polaramine;(gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen (Z)-maleate;2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (S)-, (Z)-2-butenedioate (1:1);but-2-enedioic acid; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (+)-;2-Pyridinepropanamine,?-(4-chlorophenyl)-N,- N-dimethyl-,(?S)-,(2Z)-2-butenedioate (1:1);Dexchlorpheniramine maleate;S-(+)-Chlorpheniramine maleate;

Identification
NameDexchloropheniramine maleate
CAS2438-32-6
SynonymsDexchlorpheniramine Maleate BP/USP;(+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate (1:1);D-Chlorpheniramine maleate;Polaramine (TN);(+)-Chlorpheniramine maleate;Polaramine;(gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen (Z)-maleate;2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (S)-, (Z)-2-butenedioate (1:1);but-2-enedioic acid; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (+)-;2-Pyridinepropanamine,?-(4-chlorophenyl)-N,- N-dimethyl-,(?S)-,(2Z)-2-butenedioate (1:1);Dexchlorpheniramine maleate;S-(+)-Chlorpheniramine maleate;
EINECS(EC#)219-450-6
Molecular FormulaC16H19ClN2•C4H4O4
Molecular Weight390.90
Chemical Properties
AppearanceWhite or almost white, crystalline powder
storage tempRefrigerator
Safety Data

Hazard T: Toxic;
Risk R25
Safety

Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl and NOx.
Safety Information of Polaramine maleate (2438-32-6):
Hazard Codes: T
T: Toxic
Risk Statements: 25
25: Toxic if swallowed 
Safety Statements: 36/37/39-45
36/37/39: Wear suitable protective clothing, gloves and eye/face protection 
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: US6504000


Toxicity
1.    

orl-rat LD50:267 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.
2.    

ipr-rat LD50:119 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.
3.    

orl-mus LD50:189 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.
4.    

ipr-mus LD50:117 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.
5.    

ivn-mus LD50:28 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.
6.    

orl-gpg LD50:240 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347.

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