5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, hydrochloride (1:2) cas no:24853-80-3
Synonyms: 5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, dihydrochloride (8CI,9CI);2-(4-Methylpiperazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;2-(4-Methylpipirazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride; Azafen;Azaphen
Name5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, hydrochloride (1:2)
CAS24853-80-3
Synonyms5H-Pyridazino[3,4-b][1,4]benzoxazine,5-methyl-3-(4-methyl-1-piperazinyl)-, dihydrochloride (8CI,9CI);2-(4-Methylpiperazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride;2-(4-Methylpipirazinyl)-10-methyl-3,4-diazaphenoxazine dihydrochloride; Azafen;Azaphen
Molecular FormulaC16H19 N5 O . 2 Cl H
Molecular Weight 333.86
Safety
Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. An antidepressant.
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orl-rat LD50:1 g/kg
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ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
| 2. |
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scu-rat LD50:490 mg/kg
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ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
| 3. |
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ivn-rat LD50:48 mg/kg
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ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
| 4. |
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orl-mus LD50:700 mg/kg
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PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 4 (1970),118. |
| 5. |
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scu-mus LD50:330 mg/kg
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ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
| 6. |
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ivn-mus LD50:63 mg/kg
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RPTOAN Russian Pharmacology and Toxicology. Translation of FATOAO. 37 (1974),2. |
| 7. |
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orl-cat LD50:200 mg/kg
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ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. 114 (1975),787. |
