Clobetasol propionate cas no:25122-46-7
Synonyms: Pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11b,17-dihydroxy-16b-methyl-,17-propionate (8CI);21-Chloro-21-deoxybetamethasone 17-propionate;CCl 4725;CGP 9555;Clobederm;Clobesol;Clobetasol 17-propionate;Clobex;Dermoval;Dermovate;Dermoxinale;GR 2/925;Karison;Olux;Skin Cap;Temovate;Pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11b,16b)-;
NameClobetasol propionate
CAS25122-46-7
SynonymsPregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11b,17-dihydroxy-16b-methyl-,17-propionate (8CI);21-Chloro-21-deoxybetamethasone 17-propionate;CCl 4725;CGP 9555;Clobederm;Clobesol;Clobetasol 17-propionate;Clobex;Dermoval;Dermovate;Dermoxinale;GR 2/925;Karison;Olux;Skin Cap;Temovate;Pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11b,16b)-;
EINECS(EC#)246-634-3
Molecular FormulaC25H32ClFO5
Molecular Weight466.969983
AppearanceWhite Crystalline Powder
refractive index1.56
Hazard Xi:Irritant
Risk R36/37/38
Safety
Hazard Codes:Xi 
Risk Statements:36/37/38
36/37/38:Irritating to eyes, respiratory system and skin??
Safety Statements:26-36
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:Wear suitable protective clothing
Poison by subcutaneous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F? and Cl?.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
118mg/kg (118mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 241, 1982. |
| mouse |
LD50 |
oral |
> 3gm/kg (3000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 241, 1982. |
| mouse |
LD50 |
subcutaneous |
81700ug/kg (81.7mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 241, 1982. |
| rat |
LD50 |
intraperitoneal |
351mg/kg (351mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 241, 1982. |
| rat |
LD50 |
oral |
> 3gm/kg (3000mg/kg) |
? |
Drugs in Japan Vol. 6, Pg. 241, 1982. |
| rat |
LD50 |
subcutaneous |
366mg/kg (366mg/kg) |
? |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 9, Pg. 1066, 1978. |
