25122-57-0|Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)-Products Supply

Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)- cas no:25122-57-0

Synonyms: Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-17-hydroxy-16b-methyl-, butyrate (8CI);Butyric acid, ester with21-chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione (8CI);CCl 5537;Clobetasone17-butyrate;Emovate;Eumovate;GR 2/1214;Kindavate;Molivate;SN 203;

Identification

NamePregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)-
CAS25122-57-0
SynonymsPregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-17-hydroxy-16b-methyl-, butyrate (8CI);Butyric acid, ester with21-chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione (8CI);CCl 5537;Clobetasone17-butyrate;Emovate;Eumovate;GR 2/1214;Kindavate;Molivate;SN 203;
EINECS(EC#)246-635-9
Molecular FormulaC26H32ClFO5
Molecular Weight478.99

Chemical Properties

refractive index1.551

Safety Data

Hazard Xn:Harmful
Risk R40
Safety

Hazard Codes: Xn
Risk Statements: 40
40: Limited evidence of a carcinogenic effect
Safety Statements: 22-36
22: Do not breathe dust
36: Clobetasone butyrate (25122-57-0) used,please wear suitable protective clothing .
RTECS : TU4154083

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	500mg/kg (500mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983.
mouse	LD50	oral	> 6gm/kg (6000mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
mouse	LD50	subcutaneous	> 3600mg/kg (3600mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
rat	LD50	intraperitoneal	1510mg/kg (1510mg/kg)	endocrine: other changes blood: changes in spleen blood: other changes	Journal of Toxicological Sciences. Vol. 5, Pg. 45, 1980.
rat	LD50	oral	> 6gm/kg (6000mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
rat	LD50	subcutaneous	> 2600mg/kg (2600mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.

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Melone Pharmaceutical Co., Ltd.: Tel:; Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China

Celltech Group plc: Tel:+44 1753 534655; Address: Allee de la Recherche, 60 1070 Brussels

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

Shreeji Pharma International: Tel:+91-265-3019110; Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018,

Hangzhou UNIWISE International Co.,Ltd.: Tel:+86-571-28819531; Address: E-19F, Dongqiing Building, 52 Qingchun Rd, Hangzhou, China

NANJING HERMOS SCIENCE AND TECHNOLOGY CO.,LTD.: Tel:+86-25-84795759,84795761,84795762; Address: Xinhua Manssion, 55, Zhongshan Road, Nanjing, China

TIANJIN HI-TESION BIO & CHEM CO., LTD.: Tel:+86-22-23725099; Address: C1506, WANHAO MANSION, NO. 333 BINCHUIXI ROAD, NANAKAI DISTRICT, TIANJIN, CHINA

Shenzhen Simeiquan Biotechnology Co.Ltd: Tel:86-20-18102838259; Address: Bao'an Bao'an District of Shenzhen City manhole st

Hubei Yuancheng Saichuang Technology Co., Ltd: Tel:86-27-68886732; Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China

Nanjing Bangnuo Biotechnology Co., Ltd.: Tel:86-25-52113793; Address: Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Nanjing Bangnuo Biotechnology Co., Ltd.: Tel:86-25-52113793; Address: Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu

Wuhan Senwayer Century chemical Co.,Ltd: Tel:86-27-59009407; Address: 20#Xudong Street,Wuhan China

Shanghai angewchem Co.,Ltd: Tel:86-21-50762507; Address: No. 3377, Kang Xin Road, Pudong New Area, Shanghai

Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)- cas no:25122-57-0

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