25122-57-0|Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)-Products Supply

Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)- cas no:25122-57-0

Synonyms: Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-17-hydroxy-16b-methyl-, butyrate (8CI);Butyric acid, ester with21-chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione (8CI);CCl 5537;Clobetasone17-butyrate;Emovate;Eumovate;GR 2/1214;Kindavate;Molivate;SN 203;

Identification

NamePregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)-
CAS25122-57-0
SynonymsPregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-17-hydroxy-16b-methyl-, butyrate (8CI);Butyric acid, ester with21-chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione (8CI);CCl 5537;Clobetasone17-butyrate;Emovate;Eumovate;GR 2/1214;Kindavate;Molivate;SN 203;
EINECS(EC#)246-635-9
Molecular FormulaC26H32ClFO5
Molecular Weight478.99

Chemical Properties

refractive index1.551

Safety Data

Hazard Xn:Harmful
Risk R40
Safety

Hazard Codes: Xn
Risk Statements: 40
40: Limited evidence of a carcinogenic effect
Safety Statements: 22-36
22: Do not breathe dust
36: Clobetasone butyrate (25122-57-0) used,please wear suitable protective clothing .
RTECS : TU4154083

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	500mg/kg (500mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983.
mouse	LD50	oral	> 6gm/kg (6000mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
mouse	LD50	subcutaneous	> 3600mg/kg (3600mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
rat	LD50	intraperitoneal	1510mg/kg (1510mg/kg)	endocrine: other changes blood: changes in spleen blood: other changes	Journal of Toxicological Sciences. Vol. 5, Pg. 45, 1980.
rat	LD50	oral	> 6gm/kg (6000mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.
rat	LD50	subcutaneous	> 2600mg/kg (2600mg/kg)	behavioral: somnolence (general depressed activity) blood: changes in spleen skin and appendages (skin): hair: other	Yakkyoku. Pharmacy. Vol. 35, Pg. 1473, 1984.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

GSK Corporate: Tel:+44 (0)20 8047 5000; Address: GlaxoSmithKline's global headquarters, Brentford, UK

Jiaxing Junkang Commerce & Industrial Co.,Ltd.: Tel:; Address: 88 Hefeng Road,Tanghui Industrial Park, Jiaxing,Zhejiang

Melone Pharmaceutical Co., Ltd.: Tel:; Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China

Vinchem, Inc.: Tel:+1-973-6354841; Address: Vinchem, Inc. 301 Main Street PO box 639 Chatham, NJ 07928

Jiaxing Junkang Industrial Co., Ltd.: Tel:+86-(573)-2209978; Address: No.88 Hefeng Road Tanghui Industrial Estate, Jiaxing, Zhejiang 314003,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

Guangzhou Topwork Chemical Co., Ltd.: Tel:86-20-87317062; Address: Rm.1506, North Tower. Huasheng Bldg No.102, Xianliezhong Road, GuangZhou, Guangdong,

Trust & We Co., Ltd.: Tel:86-21-61551611; Address: 601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong, Shanghai, China.

Conier Chem & Pharma Co.,Ltd.: Tel:+86-(23)-62922305; Address: 24 South Section 1, Yihuan Road, Chengdu, Sichuan 610065,

Hangzhou Sage Chemical Co., Ltd.: Tel:86-571-86818502; Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road

Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Xilin Chemical Group Co., Ltd: Tel:+86-(0)-15527136576; Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071,

Manus Aktteva: Tel:+91-(79)-65123395; Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006,

Triveni Chemicals: Tel:+91-(260)-2400022, 3258683; Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195,

Pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16b)- cas no:25122-57-0

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