257-07-8|Dibenz[b,f][1,4]oxazepineProducts Supply - Chemical intermediates Network

Dibenz[b,f][1,4]oxazepine cas no:257-07-8

Synonyms: CR; CR(lacrimator); NSC 293779

Identification

NameDibenz[b,f][1,4]oxazepine
CAS257-07-8
SynonymsCR; CR(lacrimator); NSC 293779
Molecular FormulaC13H9 N O
Molecular Weight195.23

Chemical Properties

refractive index1.625

Safety Data

Safety

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and inhalation. Experimental teratogenic and reproductive effects. A human skin and eye irritant. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LCLo	inhalation	1500mg/m3/2H (1500mg/m3)		Toxicology. Vol. 8, Pg. 347, 1977.
guinea pig	LD50	intraperitoneal	463mg/kg (463mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Toxicology. Vol. 8, Pg. 347, 1977.
guinea pig	LD50	oral	629mg/kg (629mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ATAXIA BEHAVIORAL: COMA	Toxicology. Vol. 8, Pg. 347, 1977.
hamster	LCLo	inhalation	1850mg/m3/3H (1850mg/m3)		Toxicology. Vol. 8, Pg. 347, 1977.
mouse	LCLo	inhalation	1500mg/m3/2H (1500mg/m3)		Toxicology. Vol. 8, Pg. 347, 1977.
mouse	LD50	intraperitoneal	242mg/kg (242mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
mouse	LD50	intravenous	37200ug/kg (37.2mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
mouse	LD50	oral	770mg/kg (770mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rabbit	LCLo	inhalation	1500mg/m3/2H (1500mg/m3)		Toxicology. Vol. 8, Pg. 347, 1977.
rabbit	LD50	intravenous	26mg/kg (26mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rabbit	LD50	oral	1760mg/kg (1760mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: COMA BEHAVIORAL: ATAXIA	Toxicology. Vol. 8, Pg. 347, 1977.
rabbit	LD50	skin	> 400mg/kg (400mg/kg)		Toxicology. Vol. 8, Pg. 347, 1977.
rat	LD50	intraperitoneal	164mg/kg (164mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rat	LD50	intravenous	26mg/kg (26mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,
rat	LD50	oral	563mg/kg (563mg/kg)		Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974,

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Shijiazhuang Degusai Rubber Co.,Ltd: Tel:00-86-13267830726; Address: No.223 jianshe North street ,ShijiazhuangCity,Hebei Province,China

Dibenz[b,f][1,4]oxazepine cas no:257-07-8

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