Phosphonic acid,P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1) cas no:26016-98-8
Synonyms: Phosphonicacid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)- (8CI);Phosphonicacid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-;Calcium fosfomycin;Calcium phosphonomycin;Fosfomycin calcium;Fosfomycincalcium salt;Fosmicin;Levo-phosphonomycincalcium salt;
NamePhosphonic acid,P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1)
CAS26016-98-8
SynonymsPhosphonicacid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)- (8CI);Phosphonicacid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-;Calcium fosfomycin;Calcium phosphonomycin;Fosfomycin calcium;Fosfomycincalcium salt;Fosmicin;Levo-phosphonomycincalcium salt;
EINECS(EC#)247-408-7
Molecular FormulaC3H5CaO4P（· H2O）
Molecular Weight194.15
AppearanceWhite crystal powder, tasteless
storage temp2-8°C
Safety
Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of POx. See also CALCIUM COMPOUNDS.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
994mg/kg (994mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 811, 1980. |
| mouse |
LD50 |
oral |
> 3500mg/kg (3500mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 786, 1982. |
| mouse |
LD50 |
subcutaneous |
> 3500mg/kg (3500mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 786, 1982. |
| rat |
LD50 |
intraperitoneal |
1036mg/kg (1036mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 785, 1982. |
| rat |
LD50 |
oral |
> 7gm/kg (7000mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 786, 1982. |
| rat |
LD50 |
subcutaneous |
> 3500mg/kg (3500mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 786, 1982. |
