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Home > products > 8,10a-Ethano-11,3,6a-ethanylylidene-8H-indeno[2,1-b]azocine-7,10-diol,1-ethyldodecahydro-3-methyl-9-methylene-,(3R,6aS,6bS,7S,8R,10R,10aS,11R,11aR,13R)-

8,10a-Ethano-11,3,6a-ethanylylidene-8H-indeno[2,1-b]azocine-7,10-diol,1-ethyldodecahydro-3-methyl-9-methylene-,(3R,6aS,6bS,7S,8R,10R,10aS,11R,11aR,13R)- cas no:26166-37-0

Synonyms: 7,20-Cycloatidane-11,15-diol,16,17-didehydro-21-ethyl-4-methyl-, (11b,15b)-; Denudatine (6CI,7CI,8CI);8,10a-Ethano-11,3,6a-ethanylylidene-8H-indeno[2,1-b]azocine-7,10-diol,1-ethyldodecahydro-3-methyl-9-methylene-, [3R-(3a,6aa,6ba,7a,8b,10a,10ab,11a,11ab,13R*)]-

Identification
Name8,10a-Ethano-11,3,6a-ethanylylidene-8H-indeno[2,1-b]azocine-7,10-diol,1-ethyldodecahydro-3-methyl-9-methylene-,(3R,6aS,6bS,7S,8R,10R,10aS,11R,11aR,13R)-
CAS26166-37-0
Synonyms7,20-Cycloatidane-11,15-diol,16,17-didehydro-21-ethyl-4-methyl-, (11b,15b)-; Denudatine (6CI,7CI,8CI);8,10a-Ethano-11,3,6a-ethanylylidene-8H-indeno[2,1-b]azocine-7,10-diol,1-ethyldodecahydro-3-methyl-9-methylene-, [3R-(3a,6aa,6ba,7a,8b,10a,10ab,11a,11ab,13R*)]-
Molecular FormulaC22H33 N O2
Molecular Weight343.56
Chemical Properties
refractive index1.62
Safety Data

Safety

Poison by ingestion and intravenous routes. When Denudatine (CAS NO.26166-37-0) is heated to decomposition, it emits toxic fumes of NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 128mg/kg (128mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 104, 1982.
mouse LD50 oral 290mg/kg (290mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 104, 1982.
rat LD50 intravenous 130mg/kg (130mg/kg) CARDIAC: CHANGE IN RATE Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 3, Pg. 104, 1982.

 

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