26328-04-1|Cinepazide maleateProducts Supply - Chemical intermediates Network

Cinepazide maleate cas no:26328-04-1

Synonyms: Piperazine,1-[2-oxo-2-(1-pyrrolidinyl)ethyl]- 4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2- propenyl]-,(2Z)-2-butenedioate (1:1);1-(2-Oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)piperazine (Z)-2-butenedioate (1:1);MD 67350;Vasodistal;Brendil;1-(4-((3,4,5-Trimethoxycinnamoyl)-1-piperazinyl)acetyl)pyrrolidine maleate;1-((1-Pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine maleate;Piperazine, 1-((1-pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)-, maleate;Cinepazide maleate (JAN);

Identification

NameCinepazide maleate
CAS26328-04-1
SynonymsPiperazine,1-[2-oxo-2-(1-pyrrolidinyl)ethyl]- 4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2- propenyl]-,(2Z)-2-butenedioate (1:1);1-(2-Oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)piperazine (Z)-2-butenedioate (1:1);MD 67350;Vasodistal;Brendil;1-(4-((3,4,5-Trimethoxycinnamoyl)-1-piperazinyl)acetyl)pyrrolidine maleate;1-((1-Pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine maleate;Piperazine, 1-((1-pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)-, maleate;Cinepazide maleate (JAN);
EINECS(EC#)247-613-1
Molecular FormulaC₂₂H₃₁N₃O₅^.C₄H₄O₄
Molecular Weight533.57

Chemical Properties

AppearanceWhite or off-white crystalline powder.

Safety Data

Safety

Moderately toxic by ingestion, subcutaneous, and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	617mg/kg (617mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC	Therapie. Vol. 29, Pg. 29, 1974.
mouse	LD50	oral	1gm/kg (1000mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC	Therapie. Vol. 29, Pg. 29, 1974.
mouse	LD50	subcutaneous	946mg/kg (946mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 407, 1979.
rat	LD50	intravenous	414mg/kg (414mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC	Therapie. Vol. 29, Pg. 29, 1974.
rat	LD50	oral	1310mg/kg (1310mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: ANTIPSYCHOTIC	Therapie. Vol. 29, Pg. 29, 1974.
rat	LD50	subcutaneous	710mg/kg (710mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 407, 1979.

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China Langchem Inc.: Tel:+86-(21)-58956006; Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203,

Beijing HuameiHuli Biochem Ltd: Tel:010-86181995; Address: Beijing TongZhou District

Cinepazide maleate cas no:26328-04-1

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