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Phosphorothioic acid,O-(4-cyanophenyl) O,O-dimethyl ester cas no:2636-26-2

Synonyms: Phosphorothioicacid, O,O-dimethyl ester, O-ester with p-hydroxybenzonitrile (7CI,8CI);Phosphorothioic acid, O-p-cyanophenyl O,O-dimethyl ester (6CI); BAY 34727;CYAP; Ciafos; Cyanofos; Cyanophos; Cyanox; O,O-Dimethyl O-(4-cyanophenyl)phosphorothioate; O,O-Dimethyl O-(p-cyanophenyl) phosphorothioate; S 4084;Sumitomo S 4084

Identification
NamePhosphorothioic acid,O-(4-cyanophenyl) O,O-dimethyl ester
CAS2636-26-2
SynonymsPhosphorothioicacid, O,O-dimethyl ester, O-ester with p-hydroxybenzonitrile (7CI,8CI);Phosphorothioic acid, O-p-cyanophenyl O,O-dimethyl ester (6CI); BAY 34727;CYAP; Ciafos; Cyanofos; Cyanophos; Cyanox; O,O-Dimethyl O-(4-cyanophenyl)phosphorothioate; O,O-Dimethyl O-(p-cyanophenyl) phosphorothioate; S 4084;Sumitomo S 4084
EINECS(EC#)220-130-3
Molecular FormulaC9H10 N O3 P S
Molecular Weight243.23
Chemical Properties
refractive index1.554
storage temp0-6°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Poison. A cholinesterase inhibitor.
Risk R21/22
Safety

Safety Information of Cyanophos (CAS NO.2636-26-2):
Hazard Codes: Xn,N
Risk Statements: 21/22-50/53
21:  Harmful in contact with skin 
22:  Harmful if swallowed 
50:  Very Toxic to aquatic organisms
53:  May cause long-term adverse effects in the aquatic environment
Safety Statements: 36/37-60-61
36:  Wear suitable protective clothing  
37:  Wear suitable gloves
60:  This material and/or its container must be disposed of as hazardous waste 
61:  Avoid release to the environment. Refer to special instructions safety data sheet 


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 3mg/kg (3mg/kg)   Journal de Toxicologie Clinique et Experimentale. Vol. 6(3), Pg. 175, 1986.
chicken LD50 oral 23500ug/kg (23.5mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
mammal (species unspecified) LD50 skin 2010mg/kg (2010mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 21(7), Pg. 34, 1977.
mouse LD50 intraperitoneal 350mg/kg (350mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 oral 720mg/kg (720mg/kg)   Yakkyoku. Pharmacy. Vol. 37, Pg. 427, 1986.
mouse LD50 skin > 2gm/kg (2000mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 subcutaneous 1080mg/kg (1080mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
mouse LD50 unreported 720mg/kg (720mg/kg)   Rinsho Shinkeigaku. Clinical Neurology. Vol. 23, Pg. 101, 1983.
rat LD50 oral 215mg/kg (215mg/kg)   Agricultural and Biological Chemistry. Vol. 26, Pg. 257, 1962.
rat LD50 skin 800mg/kg (800mg/kg)   "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 62, 1976.
rat LD50 unreported 580mg/kg (580mg/kg)   Rinsho Shinkeigaku. Clinical Neurology. Vol. 23, Pg. 101, 1983.

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Billiken International Holding Ltd.
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Billiken International Holding Co., Ltd
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Hunan Changsha Chemfar Economy & Trade Corp. Ltd.
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DanYang HaiShun Chemical Co.,Ltd.
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Advanced Technology & Industrial Co., Ltd.
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