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1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]- cas no:2709-56-0

Synonyms: 1-Piperazineethanol,4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]- (7CI,8CI);2-(Trifluoromethyl)-9-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propylidene]thiaxanthen;2-Trifluoromethyl-9-(3-[4-(2-hydroxyethyl)-1-piperazinyl]propylidene)thioxanthene;4-[3-[2-(Trifluoromethyl)thioxanthen-9-ylidene]propyl]-1-piperazineethanol;Fluanxol;Flupenthixol;Flupentixol;Fluxanxol;LC 44;N 7009;Siplaril;

Identification
Name1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-
CAS2709-56-0
Synonyms1-Piperazineethanol,4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]- (7CI,8CI);2-(Trifluoromethyl)-9-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propylidene]thiaxanthen;2-Trifluoromethyl-9-(3-[4-(2-hydroxyethyl)-1-piperazinyl]propylidene)thioxanthene;4-[3-[2-(Trifluoromethyl)thioxanthen-9-ylidene]propyl]-1-piperazineethanol;Fluanxol;Flupenthixol;Flupentixol;Fluxanxol;LC 44;N 7009;Siplaril;
EINECS(EC#)220-304-9
Molecular FormulaC23H25F3N2OS
Molecular Weight434.56
Chemical Properties
Appearancewhite or off-white solid
refractive index1.607
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: central nervous system effects. When heated to decomposition it emits very toxic fumes of F, NOx, and SOx.
Hazard Codes:
HarmfulXn
Risk Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
Safety Statements:
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TL9900000


Toxicity
1.    

orl-chd TDLo:900 µg/kg:CNS

    DICPBB    Drug Intelligence and Clinical Pharmacy. 15 (1981),388.
2.    

orl-hmn TDLo:367 µg/kg/12D-I:CNS

    ARZNAD    Arzneimittel-Forschung. Drug Research. 22 (1972),93.
3.    

orl-mus LD50:300 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 23 (1980),878.
4.    

ipr-mus LD50:150 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 27 (1977),2121.
5.    

ivn-mus LD50:87 mg/kg

    APTOA6    Acta Pharmacologica et Toxicologica. 41 (1977),369.

supplier list

TopChem Laboratories Limited
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TYSChemical Co.,Ltd
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HangZhou Peak Chemical Co.,Ltd
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Shreeji Pharma International
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Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018,
Beijing Krohesin Technology Co., Ltd.
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ACIC Fine Chemicals Inc.
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Address: 11772 West Sample Road, Coral Springs, Florida 33065,
Quilin Chemicals Development, Inc.
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Address: 6956 Country Lakes Circle, Sarasota, Florida 34243,
Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
Jinan Haohua Industry Co., Ltd.
Tel:0086-531-58773055
Address: No.59 Gongye South RD
Shandong united-rising pharmaceutical cooperation.,ltd.
Tel:008653187965009
Address: 171No., Jing5 Road, Shizhong District, Jinan, China
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
Boc Sciences
Tel:1-631-5046093
Address: 45-16 Ramsey Road Shirley, NY 11967, USA
Xuzhou Bestenchem Technology Company Limited.
Tel:+86-(516)-8396-3237, 8396-1767
Address: Zhongshan North Road, Xuzhou, Jiangsu 221006,

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