Tilidine hydrochloride hemihydrate cas no:27107-79-5

NameTilidine hydrochloride hemihydrate
CAS27107-79-5
Synonyms3-Cyclohexene-1-carboxylicacid, 2-(dimethylamino)-1-phenyl-, ethyl ester, hydrochloride, (1R,2S)-rel-(9CI); 3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethylester, hydrochloride, trans-; 3-Cyclohexene-1-carboxylic acid,2-(dimethylamino)-1-phenyl-, ethyl ester, hydrochloride, trans-(?à)- (8CI); DL50; Tilidate;Tilidin; Tilidine hydrochloride; Valoron; W 5759A; dl-trans-Tilidinehydrochloride
EINECS(EC#)248-226-0
Molecular FormulaC17H23 N O2 . Cl H
Molecular Weight309.87

Safety

Poison by ingestion, subcutaneous, and intravenous routes. Experimental reproductive effects. An analgesic. When heated to decomposition it emits very toxic fumes of HCl and NO_x.

1.		orl-rat LD50:418 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
2.		scu-rat LD50:400 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
3.		ivn-rat LD50:74 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
4.		orl-mus LD50:437 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
5.		scu-mus LD50:490 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
6.		ivn-mus LD50:52 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.
7.		orl-dog LD50:500 mg/kg		ARZNAD    Arzneimittel-Forschung. Drug Research. 20 (1970),977.