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Levobupivacaine hydrochloride cas no:27262-48-2

Synonyms: 2-Piperidinecarboxamide,1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- (9CI);2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride,(S)-;2',6'-Pipecoloxylidide, 1-butyl-, monohydrochloride, (-)- (8CI);(-)-Bupivacaine monohydrochloride;(S)-(-)-Bupivacaine monohydrochloride;Chirocaine;Popscaine;Levobupivacaine HCL;

Identification
NameLevobupivacaine hydrochloride
CAS27262-48-2
Synonyms2-Piperidinecarboxamide,1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride, (2S)- (9CI);2-Piperidinecarboxamide, 1-butyl-N-(2,6-dimethylphenyl)-, monohydrochloride,(S)-;2',6'-Pipecoloxylidide, 1-butyl-, monohydrochloride, (-)- (8CI);(-)-Bupivacaine monohydrochloride;(S)-(-)-Bupivacaine monohydrochloride;Chirocaine;Popscaine;Levobupivacaine HCL;
Molecular FormulaC18H29ClN2O
Molecular Weight324.88866 [g/mol]
Chemical Properties
Appearancewhite crystalline powder
alpha-12.5 o (C=2, WATER)
Safety Data

Hazard T+: Very toxic;Xn: Harmful;
Risk R20/21/22
Safety

Safty information about Levobupivacaine hydrochloride (CAS NO.27262-48-2) is:
Hazard Codes:?VeryT+,HarmfulXn
Risk Statements: 26/27/28-20/21/22-28?
R26/27/28:Very toxic by inhalation, in contact with skin and if swallowed.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R28:Very toxic if swallowed.
Safety Statements: 22-36/37/39-45-36/37-53?
S22:Do not breathe dust.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.?
S53:Avoid exposure - obtain special instructions before use.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: TK6125000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LD50 intravenous 5100ug/kg (5.1mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rabbit LD50 oral 18mg/kg (18mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rabbit LD50 parenteral 207mg/kg (207mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.
rat LD50 subcutaneous 63mg/kg (63mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 200, Pg. 359, 1972.

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