Tilorone dihydrochloride cas no:27591-69-1
Synonyms: 9H-Fluoren-9-one,2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride (9CI);Fluoren-9-one,2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride (8CI);Amixinum;Amyxin;DEAE-F;RMI 10008DA;RMI 10028DA;Tilorone hydrochloride;
NameTilorone dihydrochloride
CAS27591-69-1
Synonyms9H-Fluoren-9-one,2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride (9CI);Fluoren-9-one,2,7-bis[2-(diethylamino)ethoxy]-, dihydrochloride (8CI);Amixinum;Amyxin;DEAE-F;RMI 10008DA;RMI 10028DA;Tilorone hydrochloride;
Molecular FormulaC25H36Cl2N2O3
Molecular Weight483.53
Appearanceorange yellow crystal powder
Hazard Xi: Irritant;
Risk R20/21/22;R36/37/38;R40
Safety
Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. Human systemic effects by ingestion: somnolence, anorexia, hypermotility and diarrhea. Mutation data reported. When heated to decomposition it emits very toxic fumes of HCl and NOx.Safety information of Tilorone dihydrochloride (CAS NO.27591-69-1):
Hazard Codes:??
Xn
Risk Statements:
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
36/37/38: Irritating to eyes, respiratory system and skin
40: Limited evidence of a carcinogenic effect
Safety Statements:
7: Keep container tightly closed
22: Do not breathe dust
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39: Wear suitable gloves and eye/face protection
WGK Germany:?3
RTECS:?LL9000000
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dnd-esc 20 μmol/L
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MUREAV ?? Mutation Research. 89 (1981),95. |
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dni-mus:leu 14,600?μg/L
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INNDDK ?? Investigational New Drugs. The Journal of New Anticancer Agents. 1 (1983),103. |
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orl-hmn TDLo:4?mg/kg:CNS,GIT
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CCROBU ?? Cancer Chemotherapy Reports, Part 1. 57 (1973),209. |
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orl-rat LD50:852?mg/kg
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SCIEAS ?? Science. 169 (1970),1213. |
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ipr-rat LD50:244?mg/kg
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SCIEAS ?? Science. 169 (1970),1213. |
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orl-mus LD50:959?mg/kg
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SCIEAS ?? Science. 169 (1970),1213. |
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ipr-mus LD50:145?mg/kg
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SCIEAS ?? Science. 169 (1970),1213. |
