Erythromycin,3''-O-demethyl-6-O-[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]- cas no:28022-11-9
Synonyms: MegalomicinA (8CI); Oxacyclotetradecane, megalomicin A deriv.; Antibiotic XK 41C; Sch13430;[3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-3,5,7,9,11,13-hexamethyl-7-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]oxy]-6-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
NameErythromycin,3''-O-demethyl-6-O-[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]-
CAS28022-11-9
SynonymsMegalomicinA (8CI); Oxacyclotetradecane, megalomicin A deriv.; Antibiotic XK 41C; Sch13430;[3R-(3R*,4S*,5S*,6R*,7R*,9R*,11R*,12R*,13S*,14R*)]-4-[(2,6-Dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-3,5,7,9,11,13-hexamethyl-7-[[2,3,6-trideoxy-3-(dimethylamino)-a-L-ribo-hexopyranosyl]oxy]-6-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
Molecular FormulaC44H80 N2 O15
Molecular Weight877.26
refractive index1.549
Safety
Poison by intraperitoneal route. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
350mg/kg (350mg/kg) |
|
Journal of Antibiotics. Vol. 25, Pg. 641, 1972. |
| mouse |
LD50 |
oral |
7500mg/kg (7500mg/kg) |
|
Journal of Antibiotics. Vol. 22, Pg. 253, 1969. |
| mouse |
LD50 |
subcutaneous |
7gm/kg (7000mg/kg) |
|
Journal of Antibiotics. Vol. 25, Pg. 641, 1972. |
